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Mechanistic target of rapamycin complex 1 orchestrates the interplay between hepatocytes and Kupffer cells to determine the outcome of immune-mediated hepatitis

The cell-cell interaction between hepatocytes and Kupffer cells (KCs) is crucial for maintaining liver homeostasis, and the loss of KCs and hepatocytes is known to represent a common pathogenic phenomenon in autoimmune hepatitis. Until now, the mechanisms of cell-cell interaction between hepatocytes...

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Detalles Bibliográficos
Autores principales: Sun, Xiaoli, Ni, Yajie, Lu, Qingmiao, Liang, Yan, Gu, Mengru, Xue, Xian, Dai, Chunsun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9734196/
https://www.ncbi.nlm.nih.gov/pubmed/36494334
http://dx.doi.org/10.1038/s41419-022-05487-0

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