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TBX2 specifies and maintains inner hair and supporting cell fate in the Organ of Corti

The auditory function of the mammalian cochlea relies on two types of mechanosensory hair cells and various non-sensory supporting cells. Recent studies identified the transcription factors INSM1 and IKZF2 as regulators of outer hair cell (OHC) fate. However, the transcriptional regulation of the di...

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Detalles Bibliográficos
Autores principales: Kaiser, Marina, Lüdtke, Timo H., Deuper, Lena, Rudat, Carsten, Christoffels, Vincent M., Kispert, Andreas, Trowe, Mark-Oliver
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9734556/
https://www.ncbi.nlm.nih.gov/pubmed/36494345
http://dx.doi.org/10.1038/s41467-022-35214-4