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Interpretable and tractable models of transcriptional noise for the rational design of single-molecule quantification experiments
The question of how cell-to-cell differences in transcription rate affect RNA count distributions is fundamental for understanding biological processes underlying transcription. Answering this question requires quantitative models that are both interpretable (describing concrete biophysical phenomen...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9734650/ https://www.ncbi.nlm.nih.gov/pubmed/36494337 http://dx.doi.org/10.1038/s41467-022-34857-7 |