High-throughput robust single-cell DNA methylation profiling with sciMETv2

DNA methylation is a key epigenetic property that drives gene regulatory programs in development and disease. Current single-cell methods that produce high quality methylomes are expensive and low throughput without the aid of extensive automation. We previously described a proof-of-principle techni...

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Detalles Bibliográficos
Autores principales: Nichols, Ruth V., O’Connell, Brendan L., Mulqueen, Ryan M., Thomas, Jerushah, Woodfin, Ashley R., Acharya, Sonia, Mandel, Gail, Pokholok, Dmitry, Steemers, Frank J., Adey, Andrew C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9734657/
https://www.ncbi.nlm.nih.gov/pubmed/36494343
http://dx.doi.org/10.1038/s41467-022-35374-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9734657/
https://www.ncbi.nlm.nih.gov/pubmed/36494343
http://dx.doi.org/10.1038/s41467-022-35374-3

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