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High-throughput robust single-cell DNA methylation profiling with sciMETv2
DNA methylation is a key epigenetic property that drives gene regulatory programs in development and disease. Current single-cell methods that produce high quality methylomes are expensive and low throughput without the aid of extensive automation. We previously described a proof-of-principle techni...
Autores principales: | Nichols, Ruth V., O’Connell, Brendan L., Mulqueen, Ryan M., Thomas, Jerushah, Woodfin, Ashley R., Acharya, Sonia, Mandel, Gail, Pokholok, Dmitry, Steemers, Frank J., Adey, Andrew C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9734657/ https://www.ncbi.nlm.nih.gov/pubmed/36494343 http://dx.doi.org/10.1038/s41467-022-35374-3 |
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