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Single Topical Application of 1% Clotrimazole Cream in Otomycosis

Aim: To assess the clinical improvement after single dose topical application of 1% clotrimazole cream in otomycosis and follow up for recurrence at the end of first and the third month. Materials and Methods: A prospective observational study was carried out at Government Medical college hospital....

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Autores principales: Chavan, Reshma P., Ingole, Shivraj M., Kanchewad Resident, Gajanan S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer India 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9734867/
https://www.ncbi.nlm.nih.gov/pubmed/36532230
http://dx.doi.org/10.1007/s12070-022-03206-x
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author Chavan, Reshma P.
Ingole, Shivraj M.
Kanchewad Resident, Gajanan S.
author_facet Chavan, Reshma P.
Ingole, Shivraj M.
Kanchewad Resident, Gajanan S.
author_sort Chavan, Reshma P.
collection PubMed
description Aim: To assess the clinical improvement after single dose topical application of 1% clotrimazole cream in otomycosis and follow up for recurrence at the end of first and the third month. Materials and Methods: A prospective observational study was carried out at Government Medical college hospital. Patients with KOH diagnosed fungal infection of external auditory canal were included in the study. After obtaining informed written consent from the participating patients, a detail clinical history was taken. Single topical application of 1% clotrimazole cream in otomycosis. The fungal debris was removed with the help of suction aspiration and dry mopping. A single topical application of 1% clotrimazole cream was applied under all aseptic precautions. On the 3rd day the applied cream was cleaned with help of suction under ear microscope. Patients were advised to follow up after one month and three months. During each follow up patients were assessed clinically and examined for residual fungal debris. Result: Otomycosis was seen predominantly in middle aged females, housewives and laborers by occupation. Earache was most common symptom seen in 65.2%. Unilateral involvement was seen in 89.3% cases. The most common organism isolated in otomycosis was Aspergillus niger. At the end of one month of treatment with a single dose of 1% clotrimazole cream, 102 (91.0%) patients were recovered and 10 (9.0%) patients were with persistence or recurrence of the symptoms. At the end of third month, the recovery rate was 84.8% and recurrence rate was 6.3%. Conclusion: Single topical application of 1% clotrimazole cream is effective in treating otomycosis. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1007/s12070-022-03206-x.
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spelling pubmed-97348672022-12-12 Single Topical Application of 1% Clotrimazole Cream in Otomycosis Chavan, Reshma P. Ingole, Shivraj M. Kanchewad Resident, Gajanan S. Indian J Otolaryngol Head Neck Surg Original Article Aim: To assess the clinical improvement after single dose topical application of 1% clotrimazole cream in otomycosis and follow up for recurrence at the end of first and the third month. Materials and Methods: A prospective observational study was carried out at Government Medical college hospital. Patients with KOH diagnosed fungal infection of external auditory canal were included in the study. After obtaining informed written consent from the participating patients, a detail clinical history was taken. Single topical application of 1% clotrimazole cream in otomycosis. The fungal debris was removed with the help of suction aspiration and dry mopping. A single topical application of 1% clotrimazole cream was applied under all aseptic precautions. On the 3rd day the applied cream was cleaned with help of suction under ear microscope. Patients were advised to follow up after one month and three months. During each follow up patients were assessed clinically and examined for residual fungal debris. Result: Otomycosis was seen predominantly in middle aged females, housewives and laborers by occupation. Earache was most common symptom seen in 65.2%. Unilateral involvement was seen in 89.3% cases. The most common organism isolated in otomycosis was Aspergillus niger. At the end of one month of treatment with a single dose of 1% clotrimazole cream, 102 (91.0%) patients were recovered and 10 (9.0%) patients were with persistence or recurrence of the symptoms. At the end of third month, the recovery rate was 84.8% and recurrence rate was 6.3%. Conclusion: Single topical application of 1% clotrimazole cream is effective in treating otomycosis. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1007/s12070-022-03206-x. Springer India 2022-12-08 2023-04 /pmc/articles/PMC9734867/ /pubmed/36532230 http://dx.doi.org/10.1007/s12070-022-03206-x Text en © Association of Otolaryngologists of India 2022, Springer Nature or its licensor holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law.
spellingShingle Original Article
Chavan, Reshma P.
Ingole, Shivraj M.
Kanchewad Resident, Gajanan S.
Single Topical Application of 1% Clotrimazole Cream in Otomycosis
title Single Topical Application of 1% Clotrimazole Cream in Otomycosis
title_full Single Topical Application of 1% Clotrimazole Cream in Otomycosis
title_fullStr Single Topical Application of 1% Clotrimazole Cream in Otomycosis
title_full_unstemmed Single Topical Application of 1% Clotrimazole Cream in Otomycosis
title_short Single Topical Application of 1% Clotrimazole Cream in Otomycosis
title_sort single topical application of 1% clotrimazole cream in otomycosis
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9734867/
https://www.ncbi.nlm.nih.gov/pubmed/36532230
http://dx.doi.org/10.1007/s12070-022-03206-x
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