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Picobirnaviruses in animals: a review

Picobirnaviruses (PBVs) are small non enveloped viruses with bi-segmented ds RNA. They have been observed in a wide variety of vertebrates, including mammals and birds with or without diarrhoea, as well as in sewage samples since its discovery (1988). The source of the viruses is uncertain. True hos...

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Autores principales: Reddy, Mareddy Vineetha, Gupta, Vandana, Nayak, Anju, Tiwari, Sita Prasad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9734933/
https://www.ncbi.nlm.nih.gov/pubmed/36462086
http://dx.doi.org/10.1007/s11033-022-08133-2
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author Reddy, Mareddy Vineetha
Gupta, Vandana
Nayak, Anju
Tiwari, Sita Prasad
author_facet Reddy, Mareddy Vineetha
Gupta, Vandana
Nayak, Anju
Tiwari, Sita Prasad
author_sort Reddy, Mareddy Vineetha
collection PubMed
description Picobirnaviruses (PBVs) are small non enveloped viruses with bi-segmented ds RNA. They have been observed in a wide variety of vertebrates, including mammals and birds with or without diarrhoea, as well as in sewage samples since its discovery (1988). The source of the viruses is uncertain. True hosts of PBVs and their role as primary pathogens or secondary opportunistic agents or innocuous viruses in the gut remains alien. The mechanisms by which they play a role in pathogenicity are still unclear based on the fact that they can be found in both symptomatic and asymptomatic cases. There is a need to determine their tropism since they have not only been associated with viral gastroenteritis but also been reported in the respiratory tracts of pigs. As zoonotic agents with diverse hosts, the importance of epidemiological and surveillance studies cannot be overstated. The segmented genome of PBV might pose a serious public health issue because of the possibility of continuous genetic reassortment. Aware of the growing attention being given to emerging RNA viruses, we reviewed the current knowledge on PBVs and described the current status of PBVs in animals.
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spelling pubmed-97349332022-12-12 Picobirnaviruses in animals: a review Reddy, Mareddy Vineetha Gupta, Vandana Nayak, Anju Tiwari, Sita Prasad Mol Biol Rep Review Picobirnaviruses (PBVs) are small non enveloped viruses with bi-segmented ds RNA. They have been observed in a wide variety of vertebrates, including mammals and birds with or without diarrhoea, as well as in sewage samples since its discovery (1988). The source of the viruses is uncertain. True hosts of PBVs and their role as primary pathogens or secondary opportunistic agents or innocuous viruses in the gut remains alien. The mechanisms by which they play a role in pathogenicity are still unclear based on the fact that they can be found in both symptomatic and asymptomatic cases. There is a need to determine their tropism since they have not only been associated with viral gastroenteritis but also been reported in the respiratory tracts of pigs. As zoonotic agents with diverse hosts, the importance of epidemiological and surveillance studies cannot be overstated. The segmented genome of PBV might pose a serious public health issue because of the possibility of continuous genetic reassortment. Aware of the growing attention being given to emerging RNA viruses, we reviewed the current knowledge on PBVs and described the current status of PBVs in animals. Springer Netherlands 2022-12-03 2023 /pmc/articles/PMC9734933/ /pubmed/36462086 http://dx.doi.org/10.1007/s11033-022-08133-2 Text en © The Author(s), under exclusive licence to Springer Nature B.V. 2022, Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law. This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.
spellingShingle Review
Reddy, Mareddy Vineetha
Gupta, Vandana
Nayak, Anju
Tiwari, Sita Prasad
Picobirnaviruses in animals: a review
title Picobirnaviruses in animals: a review
title_full Picobirnaviruses in animals: a review
title_fullStr Picobirnaviruses in animals: a review
title_full_unstemmed Picobirnaviruses in animals: a review
title_short Picobirnaviruses in animals: a review
title_sort picobirnaviruses in animals: a review
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9734933/
https://www.ncbi.nlm.nih.gov/pubmed/36462086
http://dx.doi.org/10.1007/s11033-022-08133-2
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