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A transient inflammatory response contributes to oxaliplatin neurotoxicity in mice

OBJECTIVES: Peripheral neuropathy is a relevant dose‐limiting adverse event that can affect up to 90% of oncologic patients with colorectal cancer receiving oxaliplatin treatment. The severity of neurotoxicity often leads to dose reduction or even premature cessation of chemotherapy. Unfortunately,...

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Detalles Bibliográficos
Autores principales: Calls, Aina, Torres‐Espin, Abel, Tormo, Marc, Martínez‐Escardó, Laura, Bonet, Núria, Casals, Ferran, Navarro, Xavier, Yuste, Víctor J., Udina, Esther, Bruna, Jordi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9735376/
https://www.ncbi.nlm.nih.gov/pubmed/36369764
http://dx.doi.org/10.1002/acn3.51691