Cargando…
MWA Performed at 5.8 GHz through ‘Side Firing’ Approach: An Exploratory Study
Recent studies have shown that ablation techniques have the potential to eradicate adrenal adenomas while preserving the functionalities of the adrenal gland and the surrounding anatomical structures. This study explores a new microwave ablation (MWA) approach operating at 5.8 GHz and using anatomic...
Autores principales: | , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9735527/ https://www.ncbi.nlm.nih.gov/pubmed/36502019 http://dx.doi.org/10.3390/s22239320 |
_version_ | 1784846788636704768 |
---|---|
author | Bottiglieri, Anna Brace, Christopher O’Halloran, Martin Farina, Laura |
author_facet | Bottiglieri, Anna Brace, Christopher O’Halloran, Martin Farina, Laura |
author_sort | Bottiglieri, Anna |
collection | PubMed |
description | Recent studies have shown that ablation techniques have the potential to eradicate adrenal adenomas while preserving the functionalities of the adrenal gland and the surrounding anatomical structures. This study explores a new microwave ablation (MWA) approach operating at 5.8 GHz and using anatomical and dielectric characteristics of the target tissue to create directional heating patterns. Numerical simulations are executed in planar and 3D adrenal models, considering two energy doses. The numerical study is refined accounting for the vaporization of the tissue water content. Ex vivo experimental evaluations on porcine adrenal models complete the study. The numerical and experimental results show that spherical ablation zones are able to cover the target for both energy doses considered. Nonetheless, most of the non-targeted tissues can be preserved from excessive heating when low energy level is used. Numerical models accounting for water vaporization are capable to foresee the experimental temperature values. This study shows that the proposed MWA directional approach operating at 5.8 GHz can be considered for creating effective and selective ablation zones. |
format | Online Article Text |
id | pubmed-9735527 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-97355272022-12-11 MWA Performed at 5.8 GHz through ‘Side Firing’ Approach: An Exploratory Study Bottiglieri, Anna Brace, Christopher O’Halloran, Martin Farina, Laura Sensors (Basel) Article Recent studies have shown that ablation techniques have the potential to eradicate adrenal adenomas while preserving the functionalities of the adrenal gland and the surrounding anatomical structures. This study explores a new microwave ablation (MWA) approach operating at 5.8 GHz and using anatomical and dielectric characteristics of the target tissue to create directional heating patterns. Numerical simulations are executed in planar and 3D adrenal models, considering two energy doses. The numerical study is refined accounting for the vaporization of the tissue water content. Ex vivo experimental evaluations on porcine adrenal models complete the study. The numerical and experimental results show that spherical ablation zones are able to cover the target for both energy doses considered. Nonetheless, most of the non-targeted tissues can be preserved from excessive heating when low energy level is used. Numerical models accounting for water vaporization are capable to foresee the experimental temperature values. This study shows that the proposed MWA directional approach operating at 5.8 GHz can be considered for creating effective and selective ablation zones. MDPI 2022-11-30 /pmc/articles/PMC9735527/ /pubmed/36502019 http://dx.doi.org/10.3390/s22239320 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Bottiglieri, Anna Brace, Christopher O’Halloran, Martin Farina, Laura MWA Performed at 5.8 GHz through ‘Side Firing’ Approach: An Exploratory Study |
title | MWA Performed at 5.8 GHz through ‘Side Firing’ Approach: An Exploratory Study |
title_full | MWA Performed at 5.8 GHz through ‘Side Firing’ Approach: An Exploratory Study |
title_fullStr | MWA Performed at 5.8 GHz through ‘Side Firing’ Approach: An Exploratory Study |
title_full_unstemmed | MWA Performed at 5.8 GHz through ‘Side Firing’ Approach: An Exploratory Study |
title_short | MWA Performed at 5.8 GHz through ‘Side Firing’ Approach: An Exploratory Study |
title_sort | mwa performed at 5.8 ghz through ‘side firing’ approach: an exploratory study |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9735527/ https://www.ncbi.nlm.nih.gov/pubmed/36502019 http://dx.doi.org/10.3390/s22239320 |
work_keys_str_mv | AT bottiglierianna mwaperformedat58ghzthroughsidefiringapproachanexploratorystudy AT bracechristopher mwaperformedat58ghzthroughsidefiringapproachanexploratorystudy AT ohalloranmartin mwaperformedat58ghzthroughsidefiringapproachanexploratorystudy AT farinalaura mwaperformedat58ghzthroughsidefiringapproachanexploratorystudy |