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Two Distinct Modes of DNA Binding by an MCM Helicase Enable DNA Translocation

A six-subunit ATPase ring forms the central hub of the replication forks in all domains of life. This ring performs a helicase function to separate the two complementary DNA strands to be replicated and drives the replication machinery along the DNA. Disruption of this helicase/ATPase ring is associ...

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Detalles Bibliográficos
Autores principales: Meagher, Martin, Myasnikov, Alexander, Enemark, Eric J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9735655/
https://www.ncbi.nlm.nih.gov/pubmed/36499022
http://dx.doi.org/10.3390/ijms232314678

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