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Research Evidence of the Role of the Glymphatic System and Its Potential Pharmacological Modulation in Neurodegenerative Diseases

The glymphatic system is a unique pathway that utilises end-feet Aquaporin 4 (AQP4) channels within perivascular astrocytes, which is believed to cause cerebrospinal fluid (CSF) inflow into perivascular space (PVS), providing nutrients and waste disposal of the brain parenchyma. It is theorised that...

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Detalles Bibliográficos
Autores principales: Verghese, Joji Philip, Terry, Alana, de Natale, Edoardo Rosario, Politis, Marios
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9735716/
https://www.ncbi.nlm.nih.gov/pubmed/36498538
http://dx.doi.org/10.3390/jcm11236964

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