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Transdermal Delivery of 2-PAM as a Tool to Increase the Effectiveness of Traditional Treatment of Organophosphate Poisoning

For the first time, the efficacy of post-exposure treatment of organophosphate (OP) poisoning was increased by transdermal delivery of acetylcholinesterase (AChE) reactivator pyridine-2-aldoxime methochloride (2-PAM) as a preventive countermeasure. By selecting the optimal ratio of components, class...

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Detalles Bibliográficos
Autores principales: Vasileva, Leysan, Gaynanova, Gulnara, Zueva, Irina, Lyubina, Anna, Amerhanova, Syumbelya, Buzyurova, Daina, Babaev, Vasily, Voloshina, Alexandra, Petrov, Konstantin, Zakharova, Lucia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9735786/
https://www.ncbi.nlm.nih.gov/pubmed/36499322
http://dx.doi.org/10.3390/ijms232314992

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