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Transdermal Delivery of 2-PAM as a Tool to Increase the Effectiveness of Traditional Treatment of Organophosphate Poisoning
For the first time, the efficacy of post-exposure treatment of organophosphate (OP) poisoning was increased by transdermal delivery of acetylcholinesterase (AChE) reactivator pyridine-2-aldoxime methochloride (2-PAM) as a preventive countermeasure. By selecting the optimal ratio of components, class...
Autores principales: | Vasileva, Leysan, Gaynanova, Gulnara, Zueva, Irina, Lyubina, Anna, Amerhanova, Syumbelya, Buzyurova, Daina, Babaev, Vasily, Voloshina, Alexandra, Petrov, Konstantin, Zakharova, Lucia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9735786/ https://www.ncbi.nlm.nih.gov/pubmed/36499322 http://dx.doi.org/10.3390/ijms232314992 |
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