Cargando…

A New MBH Adduct as an Efficient Ligand in the Synthesis of Metallodrugs: Characterization, Geometrical Optimization, XRD, Biological Activities, and Molecular Docking Studies

This article reports the synthesis, characterization, geometrical optimization, and biological studies of new MBH-based organometallic compounds of medicinal significance. The ligand (MNHA) was prepared via the Morita–Baylis–Hillman (MBH) synthetic route, from aromatic aldehyde containing multiple f...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ishfaq, Shazia, Nisar, Shazia, Iqbal, Sadaf, Ali, Saqib, Ali, Syed Tariq, Din, ElSayed, Alsaiari, Norah Salem, Dahlous, Kholood A., Javed, Muhammad Sufyan, Bocchetta, Patrizia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9735827/ https://www.ncbi.nlm.nih.gov/pubmed/36500251 http://dx.doi.org/10.3390/molecules27238150

Ejemplares similares

Stereo- and Regiospecific S(N)2′ Reaction of MBH Adducts with Isocyanoacetates: en Route to Transition-Metal-Free α-Allylation of Isocyanoacetates
por: Xie, Chunsong, et al.
Publicado: (2023)

Protein-Based Delivery Systems for Anticancer Metallodrugs: Structure and Biological Activity of the Oxaliplatin/β-Lactoglobulin Adduct
por: Monti, Daria Maria, et al.
Publicado: (2022)

Target-directed catalytic metallodrugs
por: Joyner, J.C., et al.
Publicado: (2013)

Substrate-Controlled Diversity-Oriented Synthesis of Novel Polycyclic Frameworks via [4 + 2] and [3 + 2] Annulations of Ninhydrin-Derived MBH Adducts with 3,4-Dihydroisoquinolines
por: Wang, Kaikai, et al.
Publicado: (2023)

Ruthenacarborane–Phenanthroline Derivatives as Potential Metallodrugs
por: Kellert, Martin, et al.
Publicado: (2020)

Conclusion of the Electrical Conformity Assessment Panel on the Installation of the MBH Magnet S2 in the LHC
por: Siemko, Andrzej, et al.
Publicado: (2021)

Synthesis of Substituted Isatins from the MBH Adduct of 1,5,6-Trisubstituted Isatins Using (2,4-Dinitrophenyl)hydrazine and K-10 Clay Explored as Protection–Deprotection Chemistry
por: Vadivel, Vaithiyanathan, et al.
Publicado: (2019)

Metallodrugs are unique: opportunities and challenges of discovery and development
por: Anthony, Elizabeth J., et al.
Publicado: (2020)

In Situ Nitrogen Functionalization of 2D-Ti(3)C(2)T(x)-MXenes for High-Performance Zn-Ion Supercapacitor
por: Mateen, Abdul, et al.
Publicado: (2022)

Field Quality of MBH 11-T Dipoles for HL-LHC and Impact on Beam Dynamic Aperture
por: Fiscarelli, Lucio, et al.
Publicado: (2018)

Studying the reactivity of alkyl substituted BODIPYs: first enantioselective addition of BODIPY to MBH carbonates
por: Meazza, Marta, et al.
Publicado: (2021)

DNA-Metallodrugs Interactions Signaled by Electrochemical Biosensors: An Overview
por: Ravera, Mauro, et al.
Publicado: (2007)

Metallodrugs: an approach against invasion and metastasis in cancer treatment
por: González‐Ballesteros, Mauricio M., et al.
Publicado: (2022)

Metallodrugs: Mechanisms of Action, Molecular Targets and Biological Activity
por: Ferraro, Giarita, et al.
Publicado: (2022)

New Copper-Based Metallodrugs with Anti-Invasive Capacity
por: Garufi, Alessia, et al.
Publicado: (2023)

Cancer 3D Models for Metallodrug Preclinical Testing
por: Engrácia, Diogo M., et al.
Publicado: (2023)

Metal (II) Complexes of Fluconazole: Thermal, XRD and Cytotoxicity Studies
por: Ali, Syed Imran, et al.
Publicado: (2020)

Molecular methods for assessment of non-covalent metallodrug–DNA interactions
por: Kellett, Andrew, et al.
Publicado: (2019)

Polyoxometalates as Potential Next‐Generation Metallodrugs in the Combat Against Cancer
por: Bijelic, Aleksandar, et al.
Publicado: (2018)

Cellular Transport Mechanisms of Cytotoxic Metallodrugs: An Overview beyond Cisplatin
por: Spreckelmeyer, Sarah, et al.
Publicado: (2014)

Vanga Bhasma and its XRD analysis
por: Hiremath, Rudramma, et al.
Publicado: (2010)

Synthesis, X-ray Structure and Biological Studies of New Self-Assembled Cu(II) Complexes Derived from s-Triazine Schiff Base Ligand
por: Khalil, Tarek E., et al.
Publicado: (2022)

Synthesis and Characterization of New Series of 1,3-5-Triazine Hydrazone Derivatives with Promising Antiproliferative Activity
por: Al Rasheed, Hessa H., et al.
Publicado: (2020)

Iron Metallodrugs: Stability, Redox Activity and Toxicity against Artemia salina
por: Vitorino, Hector Aguilar, et al.
Publicado: (2015)

Critical assessment of different methods for quantitative measurement of metallodrug-protein associations
por: Galvez, Luis, et al.
Publicado: (2018)

Expression proteomics study to determine metallodrug targets and optimal drug combinations
por: Lee, Ronald F. S., et al.
Publicado: (2017)

Cellular Basis of Organotin(IV) Derivatives as Anticancer Metallodrugs: A Review
por: Syed Annuar, Sharifah Nadhira, et al.
Publicado: (2021)

Thermodynamic Genome-Scale Metabolic Modeling of Metallodrug Resistance in Colorectal Cancer
por: Herrmann, Helena A., et al.
Publicado: (2021)

Relevance of Fluorinated Ligands to the Design of Metallodrugs for Their Potential Use in Cancer Treatment
por: Páez-Franco, José C., et al.
Publicado: (2022)

Selective Anticancer and Antimicrobial Metallodrugs Based on Gold(III) Dithiocarbamate Complexes
por: Abás, Elisa, et al.
Publicado: (2021)

Potent anticancer activity of a novel iridium metallodrug via oncosis
por: Ortega-Forte, Enrique, et al.
Publicado: (2022)

Elektronisch unterschreiben & Prozesse digitalisieren: Elektronische Signatur im Personalmanagement der Steiermärkischen Krankenanstaltengesellschaft m.b.H.
por: Kokoth, Franz, et al.
Publicado: (2021)

Metal catalyst-free N-allylation/alkylation of imidazole and benzimidazole with Morita–Baylis–Hillman (MBH) alcohols and acetates
por: Mhasni, Olfa, et al.
Publicado: (2023)

A Simple, Efficient, and Eco-Friendly Method for the Preparation of 3-Substituted-2,3-dihydroquinazolin-4(1H)-one Derivatives
por: Almarhoon, Zainab, et al.
Publicado: (2019)

Beyond Single-Cell Analysis of Metallodrugs by ICP-MS: Targeting Cellular Substructures
por: Galé, Audrey, et al.
Publicado: (2021)

Dynamic Intramolecular Cap for Preserving Metallodrug Integrity—A Case of Catalytic Fluoroquinolones
por: Goldmeier, Moshe N., et al.
Publicado: (2022)

Biological Use of Nanostructured Silica-Based Materials Functionalized with Metallodrugs: The Spanish Perspective
por: Díaz-García, Diana, et al.
Publicado: (2023)

Synthesis, Anti-proliferative Activity, and Molecular Docking Study of New Series of 1,3-5-Triazine Schiff Base Derivatives
por: Al Rasheed, Hessa H., et al.
Publicado: (2020)

Status and deployment of EOS XrdHttp with TPC support
por: Sindrilaru, Elvin Alin
Publicado: (2021)

Study of Micro/Nano Structuring and Mechanical Properties of KrF Excimer Laser Irradiated Al for Aerospace Industry and Surface Engineering Applications
por: , Umm-i-Kalsoom, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_a3d9k1s1vue4pbr0kia6joh6li