Cargando…

Comprehensive Transcriptomic Analysis of VISTA in Acute Myeloid Leukemia: Insights into Its Prognostic Value

The V-domain Ig suppressor of T-cell activation (VISTA) has been recognized as a critical negative regulator of antitumor immune response and is gaining growing interest as a potential pharmacological target in immunotherapy. This molecule is highly expressed in hematopoietic stem cells and myeloid...

Descripción completa

Detalles Bibliográficos
Autores principales:	Pagliuca, Simona, Gurnari, Carmelo, Zhang, Keman, Kewan, Tariq, Bahaj, Waled, Mori, Minako, Nautiyal, Ishani, Rubio, Marie Thérèse, Ferraro, Francesca, Maciejewski, Jaroslaw P., Wang, Li, Visconte, Valeria
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9735915/ https://www.ncbi.nlm.nih.gov/pubmed/36499220 http://dx.doi.org/10.3390/ijms232314885

Ejemplares similares

Is nature truly healing itself? Spontaneous remissions in Paroxysmal Nocturnal Hemoglobinuria
por: Gurnari, Carmelo, et al.
Publicado: (2021)

New approaches to idiopathic neutropenia in the era of clonal hematopoiesis
por: Ogbue, Olisaemeka D., et al.
Publicado: (2023)

A multimodal analysis of genomic and RNA splicing features in myeloid malignancies
por: Durmaz, Arda, et al.
Publicado: (2023)

Novel Scheme for Defining the Clinical Implications of TP53 Mutations in Myeloid Neoplasia
por: Bahaj, Waled, et al.
Publicado: (2023)

Novel scheme for defining the clinical implications of TP53 mutations in myeloid neoplasia
por: Bahaj, Waled, et al.
Publicado: (2023)

Deciphering the Therapeutic Resistance in Acute Myeloid Leukemia
por: Gurnari, Carmelo, et al.
Publicado: (2020)

Genomics of deletion 7 and 7q in myeloid neoplasm: from pathogenic culprits to potential synthetic lethal therapeutic targets
por: Mori, Minako, et al.
Publicado: (2023)

Alternative Splicing in Myeloid Malignancies
por: Gurnari, Carmelo, et al.
Publicado: (2021)

Large Granular Lymphocytic Leukemia: From Immunopathogenesis to Treatment of Refractory Disease
por: Zawit, Misam, et al.
Publicado: (2021)

The Interactome between Metabolism and Gene Mutations in Myeloid Malignancies
por: Gurnari, Carmelo, et al.
Publicado: (2021)

Molecular patterns identify distinct subclasses of myeloid neoplasia
por: Kewan, Tariq, et al.
Publicado: (2023)

Current Opinions on the Clinical Utility of Ravulizumab for the Treatment of Paroxysmal Nocturnal Hemoglobinuria
por: Gurnari, Carmelo, et al.
Publicado: (2021)

UBA1 Screening in Sweet Syndrome With Hematological Neoplasms Reveals a Novel Association Between VEXAS and Chronic Myelomonocytic Leukemia
por: Gurnari, Carmelo, et al.
Publicado: (2022)

From Bench to Bedside and Beyond: Therapeutic Scenario in Acute Myeloid Leukemia
por: Gurnari, Carmelo, et al.
Publicado: (2020)

Individual HLA heterogeneity and its implications for cellular immune evasion in cancer and beyond
por: Pagliuca, Simona, et al.
Publicado: (2022)

Molecular Targeted Therapy in Myelodysplastic Syndromes: New Options for Tailored Treatments
por: Pagliuca, Simona, et al.
Publicado: (2021)

Leukemia relapse via genetic immune escape after allogeneic hematopoietic cell transplantation
por: Pagliuca, Simona, et al.
Publicado: (2023)

Leukemia relapse via genetic immune escape after allogeneic hematopoietic cell transplantation
por: Pagliuca, Simona, et al.
Publicado: (2023)

Personalized Risk Schemes and Machine Learning to Empower Genomic Prognostication Models in Myelodysplastic Syndromes
por: Awada, Hussein, et al.
Publicado: (2022)

A non‐cytotoxic regimen of decitabine to treat refractory T‐cell large granular lymphocytic leukemia
por: Zawit, Misam, et al.
Publicado: (2021)

Vacuolization of hematopoietic precursors: an enigma with multiple etiologies
por: Gurnari, Carmelo, et al.
Publicado: (2021)

Digging into the HLA pockets: A new association with acute leukaemias
por: Gurnari, Carmelo, et al.
Publicado: (2022)

Applicability of 2022 classifications of acute myeloid leukemia in the real-world setting
por: Attardi, Enrico, et al.
Publicado: (2023)

P499: APPLICABILITY OF 2022 CLASSIFICATIONS OF ACUTE MYELOID LEUKEMIA IN THE REAL-WORLD SETTING
por: Attardi, Enrico, et al.
Publicado: (2023)

Clinical and basic implications of dynamic T cell receptor clonotyping in hematopoietic cell transplantation
por: Pagliuca, Simona, et al.
Publicado: (2021)

Editorial: Endocrinological sequelae of hematopoietic stem cell transplantation
por: Giudice, Valentina, et al.
Publicado: (2023)

Molecular Pathogenesis of Myelodysplastic Syndromes
por: Visconte, Valeria, et al.
Publicado: (2014)

The Role of Forkhead Box Proteins in Acute Myeloid Leukemia
por: Gurnari, Carmelo, et al.
Publicado: (2019)

Hepatitis C Infection Associated with Acquired Pure Red Cell Aplasia
por: Teague, Destini, et al.
Publicado: (2022)

Recruitment of MLL1 complex is essential for SETBP1 to induce myeloid transformation
por: Nguyen, Nhu, et al.
Publicado: (2021)

Immunotherapy in Acute Myeloid Leukemia: A Literature Review of Emerging Strategies
por: Guarnera, Luca, et al.
Publicado: (2023)

Defining the Signature of VISTA on Myeloid Cell Chemokine Responsiveness
por: Broughton, Thomas W. K., et al.
Publicado: (2019)

TET2 mutations as a part of DNA dioxygenase deficiency in myelodysplastic syndromes
por: Gurnari, Carmelo, et al.
Publicado: (2022)

The Heterogeneous Complexity of Myeloid Neoplasm: Multi-Level Approaches to Study the Disease
por: Awada, Hussein, et al.
Publicado: (2023)

P726: TET2 ALLELIC BURDEN IMPRINTS A CONTEXT-DEPENDENT PROGNOSTIC SIGNIFICANCE OF ASXL1 MUTATION IN CHRONIC MYELOMONOCYTIC LEUKAEMIA
por: Wang, Yu-Hung, et al.
Publicado: (2023)

Comprehensive quantitative proteomic profiling of the pharmacodynamic changes induced by MLN4924 in acute myeloid leukemia cells establishes rationale for its combination with azacitidine
por: Visconte, Valeria, et al.
Publicado: (2015)

Targeting STAT3-VISTA axis to suppress tumor aggression and burden in acute myeloid leukemia
por: Mo, Jianshan, et al.
Publicado: (2023)

Radiation Recall in a Patient with Intrahepatic Cholangiocarcinoma: Case Report and a Literature Review
por: Bahaj, Waled, et al.
Publicado: (2019)

The first concurrent diagnosis of acute symptomatic Babesiosis and chronic myeloid leukemia in a healthy young adult
por: Xie, Yan, et al.
Publicado: (2018)

Complete mutational spectrum of the autophagy interactome: a novel class of tumor suppressor genes in myeloid neoplasms
por: Visconte, Valeria, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_7p43bqfcr6p85rnj2f5tqsmnfc