Relevance of Plasma Homocysteine and Methylenetetrahydrofolate Reductase 677TT Genotype in Sickle Cell Disease: A Systematic Review and Meta-Analysis

We evaluated the relevance of plasma homocysteine (HC) and the TT genotype of the methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism (rs1801133) in sickle cell disease (SCD) and associated vaso-occlusive crisis (VOC) and ischemic stroke (IS). We identified in Embase and Medline 22 studie...

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Detalles Bibliográficos
Autores principales: Ames, Paul R. J., Arcaro, Alessia, Caruso, Matilde, Graf, Maria, Marottoli, Vincenzo, Gentile, Fabrizio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9736045/
https://www.ncbi.nlm.nih.gov/pubmed/36498990
http://dx.doi.org/10.3390/ijms232314641

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9736045/
https://www.ncbi.nlm.nih.gov/pubmed/36498990
http://dx.doi.org/10.3390/ijms232314641

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