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Relevance of Plasma Homocysteine and Methylenetetrahydrofolate Reductase 677TT Genotype in Sickle Cell Disease: A Systematic Review and Meta-Analysis

We evaluated the relevance of plasma homocysteine (HC) and the TT genotype of the methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism (rs1801133) in sickle cell disease (SCD) and associated vaso-occlusive crisis (VOC) and ischemic stroke (IS). We identified in Embase and Medline 22 studie...

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Detalles Bibliográficos
Autores principales:	Ames, Paul R. J., Arcaro, Alessia, Caruso, Matilde, Graf, Maria, Marottoli, Vincenzo, Gentile, Fabrizio
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9736045/ https://www.ncbi.nlm.nih.gov/pubmed/36498990 http://dx.doi.org/10.3390/ijms232314641

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