Current Radiotherapy Considerations for Nasopharyngeal Carcinoma †

SIMPLE SUMMARY: Nasopharyngeal carcinoma (NPC) is commonly treated using high-dose radiotherapy. Careful radiotherapy planning is crucial for the eradication of cancer cells while avoiding injuries to normal structures. This balance is often delicate given the complex anatomic location in which NPC is situated. This article highlights the considerations, practical pearls, and recent advances in the precise delivery of radiotherapy in NPC patients. ABSTRACT: Radiotherapy is the primary treatment modality for nasopharyngeal carcinoma (NPC). Successful curative treatment requires optimal radiotherapy planning and precise beam delivery that maximizes locoregional control while minimizing treatment-related side effects. In this article, we highlight considerations in target delineation, radiation dose, and the adoption of technological advances with the aim of optimizing the benefits of radiotherapy in NPC patients.