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The Underestimated Role of the p53 Pathway in Renal Cancer

SIMPLE SUMMARY: The TP53 tumor suppressor gene, the guardian of the genome, is mutated or has an inactive pathway in most chemo-resistant tumors. Most studies focus on the role of mutated TP53 in tumors. In this review, we discuss the role of p53 pathway alterations in renal cell carcinoma, one of t...

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Detalles Bibliográficos
Autores principales: Amendolare, Alessandra, Marzano, Flaviana, Petruzzella, Vittoria, Vacca, Rosa Anna, Guerrini, Luisa, Pesole, Graziano, Sbisà, Elisabetta, Tullo, Apollonia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9736171/
https://www.ncbi.nlm.nih.gov/pubmed/36497215
http://dx.doi.org/10.3390/cancers14235733