Cargando…
Antiarrhythmic and Inotropic Effects of Selective Na(+)/Ca(2+) Exchanger Inhibition: What Can We Learn from the Pharmacological Studies?
Life-long stable heart function requires a critical balance of intracellular Ca(2+). Several ion channels and pumps cooperate in a complex machinery that controls the influx, release, and efflux of Ca(2+). Probably one of the most interesting and most complex players of this crosstalk is the Na(+)/C...
Autores principales: | Nagy, Norbert, Tóth, Noémi, Nánási, Péter P. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9736231/ https://www.ncbi.nlm.nih.gov/pubmed/36498977 http://dx.doi.org/10.3390/ijms232314651 |
Ejemplares similares
-
The Cardiac Pacemaker Story—Fundamental Role of the Na(+)/Ca(2+) Exchanger in Spontaneous Automaticity
por: Kohajda, Zsófia, et al.
Publicado: (2020) -
Novel Na(+)/Ca(2+) Exchanger Inhibitor ORM-10962 Supports Coupled Function of Funny-Current and Na(+)/Ca(2+) Exchanger in Pacemaking of Rabbit Sinus Node Tissue
por: Kohajda, Zsófia, et al.
Publicado: (2020) -
The reverse mode of the Na(+)/Ca(2+) exchanger contributes to the pacemaker mechanism in rabbit sinus node cells
por: Tóth, Noémi, et al.
Publicado: (2022) -
Enhanced Late Na and Ca Currents as Effective Antiarrhythmic Drug Targets
por: Karagueuzian, Hrayr S., et al.
Publicado: (2017) -
Late Sodium Current Inhibitors as Potential Antiarrhythmic Agents
por: Horváth, Balázs, et al.
Publicado: (2020)