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A Comprehensive Review of Electrospun Fibers, 3D-Printed Scaffolds, and Hydrogels for Cancer Therapies

Anticancer therapies and regenerative medicine are being developed to destroy tumor cells, as well as remodel, replace, and support injured organs and tissues. Nowadays, a suitable three-dimensional structure of the scaffold and the type of cells used are crucial for creating bio-inspired organs and...

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Autores principales: Zaszczyńska, Angelika, Niemczyk-Soczynska, Beata, Sajkiewicz, Paweł
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9736375/
https://www.ncbi.nlm.nih.gov/pubmed/36501672
http://dx.doi.org/10.3390/polym14235278
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author Zaszczyńska, Angelika
Niemczyk-Soczynska, Beata
Sajkiewicz, Paweł
author_facet Zaszczyńska, Angelika
Niemczyk-Soczynska, Beata
Sajkiewicz, Paweł
author_sort Zaszczyńska, Angelika
collection PubMed
description Anticancer therapies and regenerative medicine are being developed to destroy tumor cells, as well as remodel, replace, and support injured organs and tissues. Nowadays, a suitable three-dimensional structure of the scaffold and the type of cells used are crucial for creating bio-inspired organs and tissues. The materials used in medicine are made of non-degradable and degradable biomaterials and can serve as drug carriers. Developing flexible and properly targeted drug carrier systems is crucial for tissue engineering, regenerative medicine, and novel cancer treatment strategies. This review is focused on presenting innovative biomaterials, i.e., electrospun nanofibers, 3D-printed scaffolds, and hydrogels as a novel approach for anticancer treatments which are still under development and awaiting thorough optimization.
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spelling pubmed-97363752022-12-11 A Comprehensive Review of Electrospun Fibers, 3D-Printed Scaffolds, and Hydrogels for Cancer Therapies Zaszczyńska, Angelika Niemczyk-Soczynska, Beata Sajkiewicz, Paweł Polymers (Basel) Review Anticancer therapies and regenerative medicine are being developed to destroy tumor cells, as well as remodel, replace, and support injured organs and tissues. Nowadays, a suitable three-dimensional structure of the scaffold and the type of cells used are crucial for creating bio-inspired organs and tissues. The materials used in medicine are made of non-degradable and degradable biomaterials and can serve as drug carriers. Developing flexible and properly targeted drug carrier systems is crucial for tissue engineering, regenerative medicine, and novel cancer treatment strategies. This review is focused on presenting innovative biomaterials, i.e., electrospun nanofibers, 3D-printed scaffolds, and hydrogels as a novel approach for anticancer treatments which are still under development and awaiting thorough optimization. MDPI 2022-12-02 /pmc/articles/PMC9736375/ /pubmed/36501672 http://dx.doi.org/10.3390/polym14235278 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Zaszczyńska, Angelika
Niemczyk-Soczynska, Beata
Sajkiewicz, Paweł
A Comprehensive Review of Electrospun Fibers, 3D-Printed Scaffolds, and Hydrogels for Cancer Therapies
title A Comprehensive Review of Electrospun Fibers, 3D-Printed Scaffolds, and Hydrogels for Cancer Therapies
title_full A Comprehensive Review of Electrospun Fibers, 3D-Printed Scaffolds, and Hydrogels for Cancer Therapies
title_fullStr A Comprehensive Review of Electrospun Fibers, 3D-Printed Scaffolds, and Hydrogels for Cancer Therapies
title_full_unstemmed A Comprehensive Review of Electrospun Fibers, 3D-Printed Scaffolds, and Hydrogels for Cancer Therapies
title_short A Comprehensive Review of Electrospun Fibers, 3D-Printed Scaffolds, and Hydrogels for Cancer Therapies
title_sort comprehensive review of electrospun fibers, 3d-printed scaffolds, and hydrogels for cancer therapies
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9736375/
https://www.ncbi.nlm.nih.gov/pubmed/36501672
http://dx.doi.org/10.3390/polym14235278
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