Two Single Nucleotide Polymorphisms in the Purinergic Receptor P2X7 Gene Are Associated with Disease Severity in Multiple Sclerosis

Multiple sclerosis (MS) is a chronic autoimmune inflammatory disease of the central nervous system (CNS) that leads to progressive physical disability. Recent evidence has suggested that P2X7 receptor (P2X7R)-mediated purinergic signalling pathways play a role in MS-associated neuroinflammation, pos...

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Detalles Bibliográficos
Autores principales: Guerini, Franca Rosa, Agliardi, Cristina, Bolognesi, Elisabetta, Zanzottera, Milena, Caputo, Domenico, Pasanisi, Maria Barbara, Rovaris, Marco, Clerici, Mario
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9736555/
https://www.ncbi.nlm.nih.gov/pubmed/36499708
http://dx.doi.org/10.3390/ijms232315381

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