Clinical Application of Poly(ADP-ribose) Polymerase (PARP) Inhibitors in Prostate Cancer

SIMPLE SUMMARY: Stage IV (metastatic) prostate cancer remains an incurable disease despite many treatment advances in recent years. Approximately a quarter of men with advanced prostate cancer have alterations in DNA repair pathways, namely, homologous recombination repair (HRR). Poly(ADP-ribose) po...

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Detalles Bibliográficos
Autores principales: Inderjeeth, Andrisha-Jade, Topp, Monique, Sanij, Elaine, Castro, Elena, Sandhu, Shahneen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9736565/
https://www.ncbi.nlm.nih.gov/pubmed/36497408
http://dx.doi.org/10.3390/cancers14235922

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