Properties and Potential Antiproliferative Activity of Thrombin-Binding Aptamer (TBA) Derivatives with One or Two Additional G-Tetrads

In this paper, we study the biological properties of two TBA analogs containing one and two extra G-tetrads, namely TBAG3 and TBAG4, respectively, and two further derivatives in which one of the small loops at the bottom (TBAG41S) or the large loop at the top (TBAG4GS) of the TBAG4 structure has bee...

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Detalles Bibliográficos
Autores principales: Benigno, Daniela, Virgilio, Antonella, Bello, Ivana, La Manna, Sara, Vellecco, Valentina, Bucci, Mariarosaria, Marasco, Daniela, Panza, Elisabetta, Esposito, Veronica, Galeone, Aldo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9736779/
https://www.ncbi.nlm.nih.gov/pubmed/36499249
http://dx.doi.org/10.3390/ijms232314921

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9736779/
https://www.ncbi.nlm.nih.gov/pubmed/36499249
http://dx.doi.org/10.3390/ijms232314921

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