Engineering chimeric antigen receptor T cells for solid tumour therapy

Cell‐based immunotherapy, for example, chimeric antigen receptor T (CAR‐T) cell immunotherapy, has revolutionized cancer treatment, particularly for blood cancers. However, factors such as insufficient T cell tracking, tumour heterogeneity, inhibitory tumour microenvironment (TME) and T cell exhaust...

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Detalles Bibliográficos
Autores principales: Liu, Longwei, Qu, Yunjia, Cheng, Leonardo, Yoon, Chi Woo, He, Peixiang, Monther, Abdula, Guo, Tianze, Chittle, Sarah, Wang, Yingxiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Reviews
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9736813/
https://www.ncbi.nlm.nih.gov/pubmed/36495108
http://dx.doi.org/10.1002/ctm2.1141

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