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The Real-Time Validation of the Effectiveness of Third-Generation Hyperbranched Poly(ɛ-lysine) Dendrons-Modified KLVFF Sequences to Bind Amyloid-β(1-42) Peptides Using an Optical Waveguide Light-Mode Spectroscopy System
The aggregation of cytotoxic amyloid peptides (Aβ(1-42)) is widely recognised as the cause of brain tissue degeneration in Alzheimer’s disease (AD). Indeed, evidence indicates that the deposition of cytotoxic Aβ(1-42) plaques formed through the gradual aggregation of Aβ(1-42) monomers into fibrils d...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2022
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9736926/ https://www.ncbi.nlm.nih.gov/pubmed/36502262 http://dx.doi.org/10.3390/s22239561 |