Different Molecular Forms of TFF3 in the Human Respiratory Tract: Heterodimerization with IgG Fc Binding Protein (FCGBP) and Proteolytic Cleavage in Bronchial Secretions

The polypeptide TFF3 belongs to the trefoil factor family (TFF) of lectins. TFF3 is typically secreted from mucous epithelia together with mucins. Both intestinal and salivary TFF3 mainly exist as disulfide-linked heterodimers with IgG Fc binding protein (FCGBP). Here, we investigated bronchial tiss...

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Detalles Bibliográficos
Autores principales: Weste, Jens, Houben, Till, Harder, Sönke, Schlüter, Hartmut, Lücke, Eva, Schreiber, Jens, Hoffmann, Werner
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9737082/
https://www.ncbi.nlm.nih.gov/pubmed/36499686
http://dx.doi.org/10.3390/ijms232315359

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