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EMD-57033 Augments the Contractility in Porcine Myocardium by Promoting the Activation of Myosin in Thick Filaments

Sufficient cardiac contractility is necessary to ensure the sufficient cardiac output to provide an adequate end-organ perfusion. Inadequate cardiac output and the diminished perfusion of vital organs from depressed myocardium contractility is a hallmark end-stage of heart failure. There are no avai...

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Detalles Bibliográficos
Autores principales: Jani, Vivek, Qian, Wenjing, Yuan, Shengyao, Irving, Thomas, Ma, Weikang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9737153/
https://www.ncbi.nlm.nih.gov/pubmed/36498844
http://dx.doi.org/10.3390/ijms232314517