In Vitro Study of Cytotoxic Mechanisms of Alkylphospholipids and Alkyltriazoles in Acute Lymphoblastic Leukemia Models

This study investigates the efficacy of miltefosine, alkylphospholipid, and alkyltriazolederivative compounds against leukemia lineages. The cytotoxic effects and cellular and molecular mechanisms of the compounds were investigated. The inhibitory potential and mechanism of inhibition of cathepsins...

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Detalles Bibliográficos
Autores principales: Jesus, Larissa de Oliveira Passos, de Souza, Aline Aparecida, Torquato, Heron Fernandes Vieira, Gontijo, Vanessa Silva, Pereira de Freitas, Rossimirian, Gesteira, Tarsis Ferreira, Coulson-Thomas, Vivien Jane, Torquato, Ricardo José Soares, Tanaka, Aparecida Sadae, Paredes-Gamero, Edgar Julian, Judice, Wagner Alves de Souza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9737184/
https://www.ncbi.nlm.nih.gov/pubmed/36500726
http://dx.doi.org/10.3390/molecules27238633

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