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Normoxic HIF-1α Stabilization Caused by Local Inflammatory Factors and Its Consequences in Human Coronary Artery Endothelial Cells

HIGHLIGHTS: A HIF-1α biosensor was generated to facilitate studies on the role of different agents in normoxic HIF-1α stabilization. Micromilieu factors (MFs) induce normoxic HIF-1α stabilization with two different kinetics in HCAECs. There is an unknown indirect regulation of normoxic HIF-1α stabil...

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Detalles Bibliográficos
Autores principales: Abdi Sarabi, Mohsen, Shiri, Alireza, Aghapour, Mahyar, Reichardt, Charlotte, Brandt, Sabine, Mertens, Peter R., Medunjanin, Senad, Bruder, Dunja, Braun-Dullaeus, Ruediger C., Weinert, Sönke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9737288/
https://www.ncbi.nlm.nih.gov/pubmed/36497143
http://dx.doi.org/10.3390/cells11233878

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