Cargando…

Transcriptomic Landscape and Functional Characterization of Human Induced Pluripotent Stem Cell-Derived Limbal Epithelial Progenitor Cells

Limbal stem cell deficiency (LSCD) is a complex, multifactorial disease affecting limbal epithelial progenitor cells (LEPC), which are essential for maintaining corneal stability and transparency. Human induced pluripotent stem cell-derived (hiPSC-) LEPC are a promising cell source for the treatment...

Descripción completa

Detalles Bibliográficos
Autores principales:	Polisetti, Naresh, Rapp, Julian, Liang, Paula, Dettmer-Monaco, Viviane, Bucher, Felicitas, Pruszak, Jan, Schlötzer-Schrehardt, Ursula, Cathomen, Toni, Schlunck, Günther, Reinhard, Thomas
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9737332/ https://www.ncbi.nlm.nih.gov/pubmed/36497012 http://dx.doi.org/10.3390/cells11233752

Ejemplares similares

A Decellularized Human Limbal Scaffold for Limbal Stem Cell Niche Reconstruction
por: Polisetti, Naresh, et al.
Publicado: (2021)

Isolation and enrichment of melanocytes from human corneal limbus using CD117 (c-Kit) as selection marker
por: Polisetti, Naresh, et al.
Publicado: (2020)

Efficient Isolation and Functional Characterization of Niche Cells from Human Corneal Limbus
por: Polisetti, Naresh, et al.
Publicado: (2022)

PAX6 Expression Patterns in the Adult Human Limbal Stem Cell Niche
por: Polisetti, Naresh, et al.
Publicado: (2023)

Laminin-511 and -521-based matrices for efficient ex vivo-expansion of human limbal epithelial progenitor cells
por: Polisetti, Naresh, et al.
Publicado: (2017)

Efficient Isolation and Expansion of Limbal Melanocytes for Tissue Engineering
por: Polisetti, Naresh, et al.
Publicado: (2023)

Characterization of Porcine Ocular Surface Epithelial Microenvironment
por: Polisetti, Naresh, et al.
Publicado: (2023)

Laminin-511-E8 promotes efficient in vitro expansion of human limbal melanocytes
por: Polisetti, Naresh, et al.
Publicado: (2020)

A decellularized human corneal scaffold for anterior corneal surface reconstruction
por: Polisetti, Naresh, et al.
Publicado: (2021)

P-Cadherin Is Expressed by Epithelial Progenitor Cells and Melanocytes in the Human Corneal Limbus
por: Polisetti, Naresh, et al.
Publicado: (2022)

Transcription factor profiling identifies Sox9 as regulator of proliferation and differentiation in corneal epithelial stem/progenitor cells
por: Menzel-Severing, Johannes, et al.
Publicado: (2018)

Identification, Isolation, and Characterization of Melanocyte Precursor Cells in the Human Limbal Stroma
por: Li, Shen, et al.
Publicado: (2022)

Corneal Limbal Microenvironment Can Induce Transdifferentiation of Hair Follicle Stem Cells into Corneal Epithelial-like Cells
por: Blazejewska, Ewa Anna, et al.
Publicado: (2009)

Gene expression profile of epithelial cells and mesenchymal cells derived from limbal explant culture
por: Polisetti, Naresh, et al.
Publicado: (2010)

The Limbal Epithelial Progenitors in the Limbal Niche Environment
por: Zhang, Yuan, et al.
Publicado: (2016)

Adoptive T cell therapy cures mice from active hemophagocytic lymphohistiocytosis (HLH)
por: Weißert, Kristoffer, et al.
Publicado: (2022)

Genetics and Genomics of Pseudoexfoliation Syndrome/Glaucoma
por: Schlötzer-Schrehardt, Ursula
Publicado: (2011)

Pseudoexfoliation Syndrome: The Puzzle Continues
por: Schlötzer-Schrehardt, Ursula
Publicado: (2012)

An Anti-PSMA Immunotoxin Reduces Mcl-1 and Bcl2A1 and Specifically Induces in Combination with the BAD-Like BH3 Mimetic ABT-737 Apoptosis in Prostate Cancer Cells
por: Masilamani, Anie P., et al.
Publicado: (2020)

Nucleic Acid and Non-Nucleic Acid-Based Reprogramming of Adult Limbal Progenitors to Pluripotency
por: Parameswaran, Sowmya, et al.
Publicado: (2012)

A Comparison of Methods for Isolation of Limbal Niche Cells: Maintenance of Limbal Epithelial Stem/Progenitor Cells
por: Xiao, Yu-Ting, et al.
Publicado: (2020)

Bone Morphogenetic Protein 4 (BMP4) Enhances the Differentiation of Human Induced Pluripotent Stem Cells into Limbal Progenitor Cells
por: Lee, Hyun Soo, et al.
Publicado: (2021)

PSMA-Directed CAR T Cells Combined with Low-Dose Docetaxel Treatment Induce Tumor Regression in a Prostate Cancer Xenograft Model
por: Alzubi, Jamal, et al.
Publicado: (2020)

Limbal niche cells are a potent resource of adult mesenchymal progenitors
por: Guo, Ping, et al.
Publicado: (2018)

Lessons from the Embryonic Neural Stem Cell Niche for Neural Lineage Differentiation of Pluripotent Stem Cells
por: Solozobova, Valeriya, et al.
Publicado: (2012)

HC‐HA/PTX3 from amniotic membrane reverts senescent limbal niche cells to Pax6+ neural crest progenitors to support limbal epithelial progenitors
por: Chen, Szu‐Yu, et al.
Publicado: (2021)

Human adipose-derived stem cells support the growth of limbal stem/progenitor cells
por: Mei, Hua, et al.
Publicado: (2017)

Goblet Cell Differentiation Potential in Human Corneal Limbal Epithelial Progenitor Cells In Vitro
por: Yokoo, Seiichi, et al.
Publicado: (2020)

Comparison of culture media for ex vivo cultivation of limbal epithelial progenitor cells
por: Loureiro, Renata Ruoco, et al.
Publicado: (2013)

Notch Inhibition Prevents Differentiation of Human Limbal Stem/Progenitor Cells in vitro
por: González, Sheyla, et al.
Publicado: (2019)

Wnt Signaling Is Required for the Maintenance of Human Limbal Stem/Progenitor Cells In Vitro
por: González, Sheyla, et al.
Publicado: (2019)

Arteriovenous crossing in retinal vessels of mice, rats, and pigs
por: Martin, Gottfried, et al.
Publicado: (2020)

Mesenchymal cells from limbal stroma of human eye
por: Polisetty, Naresh, et al.
Publicado: (2008)

Transcorneal freezing and topical Rho-kinase inhibitor treatment in Fuchs endothelial corneal dystrophy
por: Menzel-Severing, Johannes, et al.
Publicado: (2021)

Systemic Immunosuppression for Limbal Allograft and Allogenic Limbal Epithelial Cell Transplantation
por: Serna-Ojeda, Juan Carlos, et al.
Publicado: (2020)

Kinetics of Expansion of Human Limbal Epithelial Progenitor Cells in Primary Culture of Explants Without Feeders
por: Ghoubay-Benallaoua, Djida, et al.
Publicado: (2013)

Comparative Study of Xenobiotic-Free Media for the Cultivation of Human Limbal Epithelial Stem/Progenitor Cells
por: González, Sheyla, et al.
Publicado: (2017)

Wnt6 plays a complex role in maintaining human limbal stem/progenitor cells
por: Bonnet, Clémence, et al.
Publicado: (2021)

Comprehensive 3D epigenomic maps define limbal stem/progenitor cell function and identity
por: Li, Mingsen, et al.
Publicado: (2022)

Differentiation Trajectory of Limbal Stem and Progenitor Cells under Normal Homeostasis and upon Corneal Wounding
por: Song, Zhenwei, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_ga9sd2pleqbnbv83f4559184jv