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Therapy of Extensive Chronic Skin Defects after a Traumatic Injury Due to Microbial Contamination Using a Surface Implant Made of a Biocompatible Polycaprolactone—A Pilot Case Study

This case study describes the use of additive manufacturing technology combining a biodegradable polymer material, polycaprolactone (PCL), and innovative procedures for creating superficial wound dressing, a scaffold in the therapy of extensive contaminated skin defects caused by a traumatic injury....

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Detalles Bibliográficos
Autores principales: Findrik Balogová, Alena, Kožár, Martin, Staroňová, Radka, Schnitzer, Marek, Dancáková, Gabriela, Živčák, Jozef, Hudák, Radovan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9737423/
https://www.ncbi.nlm.nih.gov/pubmed/36501687
http://dx.doi.org/10.3390/polym14235293
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author Findrik Balogová, Alena
Kožár, Martin
Staroňová, Radka
Schnitzer, Marek
Dancáková, Gabriela
Živčák, Jozef
Hudák, Radovan
author_facet Findrik Balogová, Alena
Kožár, Martin
Staroňová, Radka
Schnitzer, Marek
Dancáková, Gabriela
Živčák, Jozef
Hudák, Radovan
author_sort Findrik Balogová, Alena
collection PubMed
description This case study describes the use of additive manufacturing technology combining a biodegradable polymer material, polycaprolactone (PCL), and innovative procedures for creating superficial wound dressing, a scaffold in the therapy of extensive contaminated skin defects caused by a traumatic injury. Chronic and contaminated wounds represent a clinical problem and require intensive wound care. The application of a temporary scaffold-facilitated bridging of the wound edges resulted in faster tissue regeneration and a shorter defect closure time, compared to other conservative and surgical methods used in therapy of chronic wounds. Although this procedure has proven to be an optimal alternative to autologous transplants, further studies with a larger number of patients would be beneficial.
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spelling pubmed-97374232022-12-11 Therapy of Extensive Chronic Skin Defects after a Traumatic Injury Due to Microbial Contamination Using a Surface Implant Made of a Biocompatible Polycaprolactone—A Pilot Case Study Findrik Balogová, Alena Kožár, Martin Staroňová, Radka Schnitzer, Marek Dancáková, Gabriela Živčák, Jozef Hudák, Radovan Polymers (Basel) Article This case study describes the use of additive manufacturing technology combining a biodegradable polymer material, polycaprolactone (PCL), and innovative procedures for creating superficial wound dressing, a scaffold in the therapy of extensive contaminated skin defects caused by a traumatic injury. Chronic and contaminated wounds represent a clinical problem and require intensive wound care. The application of a temporary scaffold-facilitated bridging of the wound edges resulted in faster tissue regeneration and a shorter defect closure time, compared to other conservative and surgical methods used in therapy of chronic wounds. Although this procedure has proven to be an optimal alternative to autologous transplants, further studies with a larger number of patients would be beneficial. MDPI 2022-12-03 /pmc/articles/PMC9737423/ /pubmed/36501687 http://dx.doi.org/10.3390/polym14235293 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Findrik Balogová, Alena
Kožár, Martin
Staroňová, Radka
Schnitzer, Marek
Dancáková, Gabriela
Živčák, Jozef
Hudák, Radovan
Therapy of Extensive Chronic Skin Defects after a Traumatic Injury Due to Microbial Contamination Using a Surface Implant Made of a Biocompatible Polycaprolactone—A Pilot Case Study
title Therapy of Extensive Chronic Skin Defects after a Traumatic Injury Due to Microbial Contamination Using a Surface Implant Made of a Biocompatible Polycaprolactone—A Pilot Case Study
title_full Therapy of Extensive Chronic Skin Defects after a Traumatic Injury Due to Microbial Contamination Using a Surface Implant Made of a Biocompatible Polycaprolactone—A Pilot Case Study
title_fullStr Therapy of Extensive Chronic Skin Defects after a Traumatic Injury Due to Microbial Contamination Using a Surface Implant Made of a Biocompatible Polycaprolactone—A Pilot Case Study
title_full_unstemmed Therapy of Extensive Chronic Skin Defects after a Traumatic Injury Due to Microbial Contamination Using a Surface Implant Made of a Biocompatible Polycaprolactone—A Pilot Case Study
title_short Therapy of Extensive Chronic Skin Defects after a Traumatic Injury Due to Microbial Contamination Using a Surface Implant Made of a Biocompatible Polycaprolactone—A Pilot Case Study
title_sort therapy of extensive chronic skin defects after a traumatic injury due to microbial contamination using a surface implant made of a biocompatible polycaprolactone—a pilot case study
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9737423/
https://www.ncbi.nlm.nih.gov/pubmed/36501687
http://dx.doi.org/10.3390/polym14235293
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