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Therapy of Extensive Chronic Skin Defects after a Traumatic Injury Due to Microbial Contamination Using a Surface Implant Made of a Biocompatible Polycaprolactone—A Pilot Case Study
This case study describes the use of additive manufacturing technology combining a biodegradable polymer material, polycaprolactone (PCL), and innovative procedures for creating superficial wound dressing, a scaffold in the therapy of extensive contaminated skin defects caused by a traumatic injury....
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9737423/ https://www.ncbi.nlm.nih.gov/pubmed/36501687 http://dx.doi.org/10.3390/polym14235293 |
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author | Findrik Balogová, Alena Kožár, Martin Staroňová, Radka Schnitzer, Marek Dancáková, Gabriela Živčák, Jozef Hudák, Radovan |
author_facet | Findrik Balogová, Alena Kožár, Martin Staroňová, Radka Schnitzer, Marek Dancáková, Gabriela Živčák, Jozef Hudák, Radovan |
author_sort | Findrik Balogová, Alena |
collection | PubMed |
description | This case study describes the use of additive manufacturing technology combining a biodegradable polymer material, polycaprolactone (PCL), and innovative procedures for creating superficial wound dressing, a scaffold in the therapy of extensive contaminated skin defects caused by a traumatic injury. Chronic and contaminated wounds represent a clinical problem and require intensive wound care. The application of a temporary scaffold-facilitated bridging of the wound edges resulted in faster tissue regeneration and a shorter defect closure time, compared to other conservative and surgical methods used in therapy of chronic wounds. Although this procedure has proven to be an optimal alternative to autologous transplants, further studies with a larger number of patients would be beneficial. |
format | Online Article Text |
id | pubmed-9737423 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-97374232022-12-11 Therapy of Extensive Chronic Skin Defects after a Traumatic Injury Due to Microbial Contamination Using a Surface Implant Made of a Biocompatible Polycaprolactone—A Pilot Case Study Findrik Balogová, Alena Kožár, Martin Staroňová, Radka Schnitzer, Marek Dancáková, Gabriela Živčák, Jozef Hudák, Radovan Polymers (Basel) Article This case study describes the use of additive manufacturing technology combining a biodegradable polymer material, polycaprolactone (PCL), and innovative procedures for creating superficial wound dressing, a scaffold in the therapy of extensive contaminated skin defects caused by a traumatic injury. Chronic and contaminated wounds represent a clinical problem and require intensive wound care. The application of a temporary scaffold-facilitated bridging of the wound edges resulted in faster tissue regeneration and a shorter defect closure time, compared to other conservative and surgical methods used in therapy of chronic wounds. Although this procedure has proven to be an optimal alternative to autologous transplants, further studies with a larger number of patients would be beneficial. MDPI 2022-12-03 /pmc/articles/PMC9737423/ /pubmed/36501687 http://dx.doi.org/10.3390/polym14235293 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Findrik Balogová, Alena Kožár, Martin Staroňová, Radka Schnitzer, Marek Dancáková, Gabriela Živčák, Jozef Hudák, Radovan Therapy of Extensive Chronic Skin Defects after a Traumatic Injury Due to Microbial Contamination Using a Surface Implant Made of a Biocompatible Polycaprolactone—A Pilot Case Study |
title | Therapy of Extensive Chronic Skin Defects after a Traumatic Injury Due to Microbial Contamination Using a Surface Implant Made of a Biocompatible Polycaprolactone—A Pilot Case Study |
title_full | Therapy of Extensive Chronic Skin Defects after a Traumatic Injury Due to Microbial Contamination Using a Surface Implant Made of a Biocompatible Polycaprolactone—A Pilot Case Study |
title_fullStr | Therapy of Extensive Chronic Skin Defects after a Traumatic Injury Due to Microbial Contamination Using a Surface Implant Made of a Biocompatible Polycaprolactone—A Pilot Case Study |
title_full_unstemmed | Therapy of Extensive Chronic Skin Defects after a Traumatic Injury Due to Microbial Contamination Using a Surface Implant Made of a Biocompatible Polycaprolactone—A Pilot Case Study |
title_short | Therapy of Extensive Chronic Skin Defects after a Traumatic Injury Due to Microbial Contamination Using a Surface Implant Made of a Biocompatible Polycaprolactone—A Pilot Case Study |
title_sort | therapy of extensive chronic skin defects after a traumatic injury due to microbial contamination using a surface implant made of a biocompatible polycaprolactone—a pilot case study |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9737423/ https://www.ncbi.nlm.nih.gov/pubmed/36501687 http://dx.doi.org/10.3390/polym14235293 |
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