Cargando…

Current Medical and Surgical Treatment of Hidradenitis Suppurativa—A Comprehensive Review

Hidradenitis suppurativa (HS) is a chronic inflammatory skin disease presenting with recurrent inflammatory lesions in intertriginous body regions. HS has a pronounced impact on patients’ quality of life and is associated with a variety of comorbidities. Treatment of HS is often complex, requiring a...

Descripción completa

Detalles Bibliográficos
Autores principales: Ocker, Lennart, Abu Rached, Nessr, Seifert, Caroline, Scheel, Christina, Bechara, Falk G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9737445/
https://www.ncbi.nlm.nih.gov/pubmed/36498816
http://dx.doi.org/10.3390/jcm11237240
_version_ 1784847290884685824
author Ocker, Lennart
Abu Rached, Nessr
Seifert, Caroline
Scheel, Christina
Bechara, Falk G.
author_facet Ocker, Lennart
Abu Rached, Nessr
Seifert, Caroline
Scheel, Christina
Bechara, Falk G.
author_sort Ocker, Lennart
collection PubMed
description Hidradenitis suppurativa (HS) is a chronic inflammatory skin disease presenting with recurrent inflammatory lesions in intertriginous body regions. HS has a pronounced impact on patients’ quality of life and is associated with a variety of comorbidities. Treatment of HS is often complex, requiring an individual approach with medical and surgical treatments available. However, especially in moderate-to-severe HS, there is an urgent need for new treatment approaches. In recent years, increased research has led to the identification of new potential therapeutic targets. This review aims to give a comprehensive and practical overview of current treatment options for HS. Furthermore, the clinically most advanced novel treatment approaches will be discussed.
format Online
Article
Text
id pubmed-9737445
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-97374452022-12-11 Current Medical and Surgical Treatment of Hidradenitis Suppurativa—A Comprehensive Review Ocker, Lennart Abu Rached, Nessr Seifert, Caroline Scheel, Christina Bechara, Falk G. J Clin Med Review Hidradenitis suppurativa (HS) is a chronic inflammatory skin disease presenting with recurrent inflammatory lesions in intertriginous body regions. HS has a pronounced impact on patients’ quality of life and is associated with a variety of comorbidities. Treatment of HS is often complex, requiring an individual approach with medical and surgical treatments available. However, especially in moderate-to-severe HS, there is an urgent need for new treatment approaches. In recent years, increased research has led to the identification of new potential therapeutic targets. This review aims to give a comprehensive and practical overview of current treatment options for HS. Furthermore, the clinically most advanced novel treatment approaches will be discussed. MDPI 2022-12-06 /pmc/articles/PMC9737445/ /pubmed/36498816 http://dx.doi.org/10.3390/jcm11237240 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Ocker, Lennart
Abu Rached, Nessr
Seifert, Caroline
Scheel, Christina
Bechara, Falk G.
Current Medical and Surgical Treatment of Hidradenitis Suppurativa—A Comprehensive Review
title Current Medical and Surgical Treatment of Hidradenitis Suppurativa—A Comprehensive Review
title_full Current Medical and Surgical Treatment of Hidradenitis Suppurativa—A Comprehensive Review
title_fullStr Current Medical and Surgical Treatment of Hidradenitis Suppurativa—A Comprehensive Review
title_full_unstemmed Current Medical and Surgical Treatment of Hidradenitis Suppurativa—A Comprehensive Review
title_short Current Medical and Surgical Treatment of Hidradenitis Suppurativa—A Comprehensive Review
title_sort current medical and surgical treatment of hidradenitis suppurativa—a comprehensive review
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9737445/
https://www.ncbi.nlm.nih.gov/pubmed/36498816
http://dx.doi.org/10.3390/jcm11237240
work_keys_str_mv AT ockerlennart currentmedicalandsurgicaltreatmentofhidradenitissuppurativaacomprehensivereview
AT aburachednessr currentmedicalandsurgicaltreatmentofhidradenitissuppurativaacomprehensivereview
AT seifertcaroline currentmedicalandsurgicaltreatmentofhidradenitissuppurativaacomprehensivereview
AT scheelchristina currentmedicalandsurgicaltreatmentofhidradenitissuppurativaacomprehensivereview
AT becharafalkg currentmedicalandsurgicaltreatmentofhidradenitissuppurativaacomprehensivereview