The Novel IGF-1R Inhibitor PB-020 Acts Synergistically with Anti-PD-1 and Mebendazole against Colorectal Cancer

SIMPLE SUMMARY: Colorectal cancer (CRC) is generally diagnosed at an advanced stage, when chemo- and targeted therapies can only achieve a limited increase in overall survival for these patients. The activation of insulin/IGF-dependent pathways has been established as a key step that contributes to...

Descripción completa

Detalles Bibliográficos
Autores principales: Kang, Bo, Zhang, Xiaobing, Wang, Weibing, She, Shiqi, Chen, Wenjie, Chen, Cheng, Wang, Yisha, Pan, Xiaoyun, Xu, Ouyuan, Wang, Yingjie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9737525/
https://www.ncbi.nlm.nih.gov/pubmed/36497233
http://dx.doi.org/10.3390/cancers14235747

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9737525/
https://www.ncbi.nlm.nih.gov/pubmed/36497233
http://dx.doi.org/10.3390/cancers14235747

Ejemplares similares