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The Novel IGF-1R Inhibitor PB-020 Acts Synergistically with Anti-PD-1 and Mebendazole against Colorectal Cancer
SIMPLE SUMMARY: Colorectal cancer (CRC) is generally diagnosed at an advanced stage, when chemo- and targeted therapies can only achieve a limited increase in overall survival for these patients. The activation of insulin/IGF-dependent pathways has been established as a key step that contributes to...
| Autores principales: | , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9737525/ https://www.ncbi.nlm.nih.gov/pubmed/36497233 http://dx.doi.org/10.3390/cancers14235747 |