Cargando…

Deletion of TNF in Winnie-APC(Min/+) Mice Reveals Its Dual Role in the Onset and Progression of Colitis-Associated Colorectal Cancer

Colorectal cancer (CRC) is among the best examples for depicting the relationship between inflammation and cancer. The introduction of new therapeutics targeting inflammatory mediators showed a marked decrease in the overall risk of CRC, although their chemopreventive potential is still debated. Spe...

Descripción completa

Detalles Bibliográficos
Autores principales:	Verna, Giulio, Liso, Marina, Cavalcanti, Elisabetta, Armentano, Raffaele, Miraglia, Alessandro, Monsurrò, Vladia, Chieppa, Marcello, De Santis, Stefania
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9737576/ https://www.ncbi.nlm.nih.gov/pubmed/36499472 http://dx.doi.org/10.3390/ijms232315145

Ejemplares similares

Winnie-APC(Min/+) Mice: A Spontaneous Model of Colitis-Associated Colorectal Cancer Combining Genetics and Inflammation
por: De Santis, Stefania, et al.
Publicado: (2020)

A Specific Mutation in Muc2 Determines Early Dysbiosis in Colitis-Prone Winnie Mice
por: Liso, Marina, et al.
Publicado: (2020)

Quercetin Exposure Suppresses the Inflammatory Pathway in Intestinal Organoids from Winnie Mice
por: Dicarlo, Manuela, et al.
Publicado: (2019)

Interleukin 1β Blockade Reduces Intestinal Inflammation in a Murine Model of Tumor Necrosis Factor–Independent Ulcerative Colitis
por: Liso, Marina, et al.
Publicado: (2022)

Phenotyping of Fecal Microbiota of Winnie, a Rodent Model of Spontaneous Chronic Colitis, Reveals Specific Metabolic, Genotoxic, and Pro-inflammatory Properties
por: Talà, Adelfia, et al.
Publicado: (2022)

Polyphenol Enriched Diet Administration During Pregnancy and Lactation Prevents Dysbiosis in Ulcerative Colitis Predisposed Littermates
por: De Santis, Stefania, et al.
Publicado: (2021)

Dysbiosis Triggers ACF Development in Genetically Predisposed Subjects
por: De Santis, Stefania, et al.
Publicado: (2021)

Winnie Puh /
Publicado: (1993)

Dr. Ephraim Winnie
Publicado: (1913)

Quercetin Administration Suppresses the Cytokine Storm in Myeloid and Plasmacytoid Dendritic Cells
por: Verna, Giulio, et al.
Publicado: (2021)

Olfactomedin 4 deletion induces colon adenocarcinoma in Apc(Min/+) mice
por: Liu, W, et al.
Publicado: (2016)

TNFα deficiency results in increased IL-1β in an early onset of spontaneous murine colitis
por: De Santis, S, et al.
Publicado: (2017)

Role of PD-L1 expression as a biomarker for GEP neuroendocrine neoplasm grading
por: Cavalcanti, Elisabetta, et al.
Publicado: (2017)

Iron Overload Mimicking Conditions Skews Bone Marrow Dendritic Cells Differentiation into MHCII(low)CD11c(+)CD11b(+)F4/80(+) Cells
por: Verna, Giulio, et al.
Publicado: (2020)

Altered miRNAs Expression Correlates With Gastroenteropancreatic Neuroendocrine Tumors Grades
por: Cavalcanti, Elisabetta, et al.
Publicado: (2020)

Administration of Reconstituted Polyphenol Oil Bodies Efficiently Suppresses Dendritic Cell Inflammatory Pathways and Acute Intestinal Inflammation
por: Cavalcanti, Elisabetta, et al.
Publicado: (2014)

Iron-Enriched Nutritional Supplements for the 2030 Pharmacy Shelves
por: Verna, Giulio, et al.
Publicado: (2021)

Freedom to choose a cure: how safe is a deadly cancer?
por: Monsurró, Vladia
Publicado: (2010)

Acarbose improved survival for Apc(+/Min) mice
por: Dodds, Sherry G., et al.
Publicado: (2020)

Total spinal anaesthesia with “Interscalene brachial plexus block by Winnie approach”
por: Verma, Anil Kumar, et al.
Publicado: (2013)

Nutritional Regimes Enriched with Antioxidants as an Efficient Adjuvant for IBD Patients under Infliximab Administration, a Pilot Study
por: Liso, Marina, et al.
Publicado: (2022)

Deficiency of SR‐B1 reduced the tumor load of colitis‐induced or APC(min) (/+)‐induced colorectal cancer
por: Chen, Qijun, et al.
Publicado: (2023)

Iatrogenic Kaposi sarcoma of the terminal ileum following short-term treatment with immunomodulators for Crohn disease: A case report
por: Stasi, Elisa, et al.
Publicado: (2019)

Microarray Analysis for a Comprehensive Immunological-Status Evaluation during Cancer Vaccine Immune Monitoring
por: Monsurrò, Vladia, et al.
Publicado: (2011)

Loss of PACS-2 delays regeneration in DSS-induced colitis but does not affect the Apc(Min) model of colorectal cancer
por: Dombernowsky, Sarah L., et al.
Publicado: (2017)

Nutritional Keys for Intestinal Barrier Modulation
por: De Santis, Stefania, et al.
Publicado: (2015)

miR-369-3p modulates inducible nitric oxide synthase and is involved in regulation of chronic inflammatory response
por: Scalavino, Viviana, et al.
Publicado: (2020)

ERK activation drives intestinal tumorigenesis in Apc(min/)(+) mice
por: Lee, Sung Hee, et al.
Publicado: (2010)

Metabolomics of Apc( Min/+ ) mice genetically susceptible to intestinal cancer
por: Dazard, Jean-Eudes J, et al.
Publicado: (2014)

OGA heterozygosity suppresses intestinal tumorigenesis in Apc(min/+) mice
por: Yang, Y R, et al.
Publicado: (2014)

Intestinal Peyer’s patches prevent tumorigenesis in Apc(Min/+) mice
por: Fujimoto, Kyoko, et al.
Publicado: (2015)

Lactonic Sophorolipids Increase Tumor Burden in Apc(min+/-) Mice
por: Callaghan, Breedge, et al.
Publicado: (2016)

Platelet status in cancer cachexia progression in Apc(Min/+) mice
por: Cunningham, Patrice, et al.
Publicado: (2023)

Potent CCR3 Receptor Antagonist, SB328437, Suppresses Colonic Eosinophil Chemotaxis and Inflammation in the Winnie Murine Model of Spontaneous Chronic Colitis
por: Filippone, Rhiannon T., et al.
Publicado: (2022)

Extra Virgin Olive Oil Extracts Modulate the Inflammatory Ability of Murine Dendritic Cells Based on Their Polyphenols Pattern: Correlation between Chemical Composition and Biological Function
por: De Santis, Stefania, et al.
Publicado: (2021)

The Chelating Ability of Plant Polyphenols Can Affect Iron Homeostasis and Gut Microbiota
por: Scarano, Aurelia, et al.
Publicado: (2023)

Adenovirus as a new agent for multiple myeloma therapies: Opportunities and restrictions
por: Raus, Svjetlana, et al.
Publicado: (2011)

Inhibition of nuclear factor-κB signaling suppresses Spint1-deletion-induced tumor susceptibility in the Apc(Min/+) model
por: Kawaguchi, Makiko, et al.
Publicado: (2016)

Secretory leukoprotease inhibitor is required for efficient quercetin-mediated suppression of TNFα secretion
por: De Santis, Stefania, et al.
Publicado: (2016)

Role of Bone Marrow-Derived Stem Cells in Polyps Development in Mice with Apc(Min/+) Mutation
por: Barone, Michele, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_e8afurb90basru0l9dt4r86uje