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Liposome-Mediated Gene Transfer in Differentiated HepaRG™ Cells: Expression of Liver Specific Functions and Application to the Cytochrome P450 2D6 Expression

The goal of this study was to establish a procedure for gene delivery mediated by cationic liposomes in quiescent differentiated HepaRG™ human hepatoma cells. We first identified several cationic lipids promoting efficient gene transfer with low toxicity in actively dividing HepG2, HuH7, BC2 and pro...

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Detalles Bibliográficos
Autores principales:	Vlach, Manuel, Coppens-Exandier, Hugo, Jamin, Agnès, Berchel, Mathieu, Scaviner, Julien, Chesné, Christophe, Montier, Tristan, Jaffrès, Paul-Alain, Corlu, Anne, Loyer, Pascal
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9737581/ https://www.ncbi.nlm.nih.gov/pubmed/36497165 http://dx.doi.org/10.3390/cells11233904

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