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Modulation of the Microglial Nogo-A/NgR Signaling Pathway as a Therapeutic Target for Multiple Sclerosis
Current therapeutics targeting chronic phases of multiple sclerosis (MS) are considerably limited in reversing the neural damage resulting from repeated inflammation and demyelination insults in the multi-focal lesions. This inflammation is propagated by the activation of microglia, the endogenous i...
Autores principales: | Nheu, Danica, Ellen, Olivia, Ye, Sining, Ozturk, Ezgi, Pagnin, Maurice, Kertadjaja, Stephen, Theotokis, Paschalis, Grigoriadis, Nikolaos, McLean, Catriona, Petratos, Steven |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9737582/ https://www.ncbi.nlm.nih.gov/pubmed/36497029 http://dx.doi.org/10.3390/cells11233768 |
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