Novel Approaches for the Solid-Phase Synthesis of Dihydroquinazoline-2(1H)-One Derivatives and Biological Evaluation as Potential Anticancer Agents

In the design of antineoplastic drugs, quinazolinone derivatives are often used as small molecule inhibitors for kinases or receptor kinases, such as the EGFR tyrosine kinase inhibitor gefitinib, p38MAP kinase inhibitor DQO-501, and BRD4 protein inhibitor PFI-1. A novel and convenient approach for t...

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Detalles Bibliográficos
Autores principales: Wang, Qiong, Pan, Ying, Luo, Hongjun, Zhang, Yanmei, Gao, Fenfei, Wang, Jinzhi, Zheng, Jinhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9737648/
https://www.ncbi.nlm.nih.gov/pubmed/36500678
http://dx.doi.org/10.3390/molecules27238577

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9737648/
https://www.ncbi.nlm.nih.gov/pubmed/36500678
http://dx.doi.org/10.3390/molecules27238577

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