Fused Pyrroles in Cholestane and Norcholestane Side Chains: Acaricidal and Plant Growth-Promoting Effects

Herein, we describe the synthesis and characterization of fused pyrroles in cholestane and norcholestane side chains derived from kryptogenin and diosgenin, respectively. Both conventional and microwave heating techniques were used to synthesize the steroidal pyrroles from primary amines, with the m...

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Autores principales: De los Santos, María G., Cua-Basulto, Marcos, Huepalcalco, Anallely, Delit, Wendy, Sandoval-Ramírez, Jesús, López-Torres, Adolfo, Ruiz-Sánchez, Esaú, Fernández-Herrera, María A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9737654/
https://www.ncbi.nlm.nih.gov/pubmed/36500556
http://dx.doi.org/10.3390/molecules27238466
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author De los Santos, María G.
Cua-Basulto, Marcos
Huepalcalco, Anallely
Delit, Wendy
Sandoval-Ramírez, Jesús
López-Torres, Adolfo
Ruiz-Sánchez, Esaú
Fernández-Herrera, María A.
author_facet De los Santos, María G.
Cua-Basulto, Marcos
Huepalcalco, Anallely
Delit, Wendy
Sandoval-Ramírez, Jesús
López-Torres, Adolfo
Ruiz-Sánchez, Esaú
Fernández-Herrera, María A.
author_sort De los Santos, María G.
collection PubMed
description Herein, we describe the synthesis and characterization of fused pyrroles in cholestane and norcholestane side chains derived from kryptogenin and diosgenin, respectively. Both conventional and microwave heating techniques were used to synthesize the steroidal pyrroles from primary amines, with the microwave method producing the highest yields. In particular, the norcholestane pyrroles were tested as acaricides against the two-spotted spider mite (Tetranychus urticae Koch) under laboratory conditions and as plant growth promoters on habanero pepper (Capsicum chinense Jacq) under greenhouse conditions.
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spelling pubmed-97376542022-12-11 Fused Pyrroles in Cholestane and Norcholestane Side Chains: Acaricidal and Plant Growth-Promoting Effects De los Santos, María G. Cua-Basulto, Marcos Huepalcalco, Anallely Delit, Wendy Sandoval-Ramírez, Jesús López-Torres, Adolfo Ruiz-Sánchez, Esaú Fernández-Herrera, María A. Molecules Article Herein, we describe the synthesis and characterization of fused pyrroles in cholestane and norcholestane side chains derived from kryptogenin and diosgenin, respectively. Both conventional and microwave heating techniques were used to synthesize the steroidal pyrroles from primary amines, with the microwave method producing the highest yields. In particular, the norcholestane pyrroles were tested as acaricides against the two-spotted spider mite (Tetranychus urticae Koch) under laboratory conditions and as plant growth promoters on habanero pepper (Capsicum chinense Jacq) under greenhouse conditions. MDPI 2022-12-02 /pmc/articles/PMC9737654/ /pubmed/36500556 http://dx.doi.org/10.3390/molecules27238466 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
De los Santos, María G.
Cua-Basulto, Marcos
Huepalcalco, Anallely
Delit, Wendy
Sandoval-Ramírez, Jesús
López-Torres, Adolfo
Ruiz-Sánchez, Esaú
Fernández-Herrera, María A.
Fused Pyrroles in Cholestane and Norcholestane Side Chains: Acaricidal and Plant Growth-Promoting Effects
title Fused Pyrroles in Cholestane and Norcholestane Side Chains: Acaricidal and Plant Growth-Promoting Effects
title_full Fused Pyrroles in Cholestane and Norcholestane Side Chains: Acaricidal and Plant Growth-Promoting Effects
title_fullStr Fused Pyrroles in Cholestane and Norcholestane Side Chains: Acaricidal and Plant Growth-Promoting Effects
title_full_unstemmed Fused Pyrroles in Cholestane and Norcholestane Side Chains: Acaricidal and Plant Growth-Promoting Effects
title_short Fused Pyrroles in Cholestane and Norcholestane Side Chains: Acaricidal and Plant Growth-Promoting Effects
title_sort fused pyrroles in cholestane and norcholestane side chains: acaricidal and plant growth-promoting effects
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9737654/
https://www.ncbi.nlm.nih.gov/pubmed/36500556
http://dx.doi.org/10.3390/molecules27238466
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