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In Silico Evaluation and In Vitro Determination of Neuroprotective and MAO-B Inhibitory Effects of Pyrrole-Based Hydrazones: A Therapeutic Approach to Parkinson’s Disease
Parkinson’s disease is a huge burden in modern medicinal practice. A serious drawback of current antiparkinsonian therapy is its symptomatic nature. This directed our investigations in the search for new more potent derivatives, affecting not only the loss of dopaminergic neurons but also the oxidat...
Autores principales: | Kondeva-Burdina, Magdalena, Mateev, Emilio, Angelov, Borislav, Tzankova, Virginia, Georgieva, Maya |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9737692/ https://www.ncbi.nlm.nih.gov/pubmed/36500572 http://dx.doi.org/10.3390/molecules27238485 |
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