Efficient Production of Fc Fusion Proteins in the Cytoplasm of Escherichia coli: Dissecting and Mitigating Redox Heterogeneity

Cost-effective production of therapeutic proteins in microbial hosts is an indispensable tool towards accessible healthcare. Many of these heterologously expressed proteins, including all antibody formats, require disulfide bond formation to attain their native and functional state. A system for cat...

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Detalles Bibliográficos
Autores principales: Tungekar, Aatir A., Ruddock, Lloyd W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9737693/
https://www.ncbi.nlm.nih.gov/pubmed/36499069
http://dx.doi.org/10.3390/ijms232314740

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9737693/
https://www.ncbi.nlm.nih.gov/pubmed/36499069
http://dx.doi.org/10.3390/ijms232314740

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