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Azumamides A-E: Isolation, Synthesis, Biological Activity, and Structure–Activity Relationship

Cyclic peptides are one of the important chemical groups in the HDAC inhibitor family. Following the success of romidepsin in the clinic, naturally occurring cyclic peptides with a hydrophilic moiety have been intensively studied to test their function as HDAC inhibitors. Azumamides A-E, isolated fr...

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Detalles Bibliográficos
Autores principales: Jo, Sooheum, Kim, Jin-Hee, Lee, Jiyeon, Park, Youngjun, Jang, Jaebong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9737774/
https://www.ncbi.nlm.nih.gov/pubmed/36500529
http://dx.doi.org/10.3390/molecules27238438