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The Spectrum of Thyroid Nodules at Kinshasa University Hospital, Democratic Republic of Congo: A Cross-Sectional Study

We analyzed the spectrum of thyroid nodules in patients attending the endocrinology unit care of the Kinshasa University Hospital and assessed their associated factors. We conducted a cross-sectional study, performing descriptive statistics and logistic regression. From the 888 enrolled patients, th...

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Autores principales: Bukasa, John Kakamba, Bayauli-Mwasa, Pascal, Mbunga, Branly Kilola, Bangolo, Ayrton, Kavula, Wivine, Mukaya, Jean, Bindingija, Joseph, M’Buyamba-Kabangu, Jean-René
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9737877/
https://www.ncbi.nlm.nih.gov/pubmed/36498276
http://dx.doi.org/10.3390/ijerph192316203
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author Bukasa, John Kakamba
Bayauli-Mwasa, Pascal
Mbunga, Branly Kilola
Bangolo, Ayrton
Kavula, Wivine
Mukaya, Jean
Bindingija, Joseph
M’Buyamba-Kabangu, Jean-René
author_facet Bukasa, John Kakamba
Bayauli-Mwasa, Pascal
Mbunga, Branly Kilola
Bangolo, Ayrton
Kavula, Wivine
Mukaya, Jean
Bindingija, Joseph
M’Buyamba-Kabangu, Jean-René
author_sort Bukasa, John Kakamba
collection PubMed
description We analyzed the spectrum of thyroid nodules in patients attending the endocrinology unit care of the Kinshasa University Hospital and assessed their associated factors. We conducted a cross-sectional study, performing descriptive statistics and logistic regression. From the 888 enrolled patients, thyroid nodules were detected in 658 patients (74.1%), as mononodules in 22.5% and multiple nodules in 77.5%. Thyroid function was normal in 71.3% cases, while hyperthyroidism and hypothyroidism were found in 26.1% and 2.6% of cases, respectively. Women were more affected than men (75.1% vs. 63.6%; p = 0.03). Patients with thyroid nodules were older (44 ± 12 vs. 38 ± 12 years; p < 0.001), with a family history of goiter (38.3% vs. 27.4%; p = 0.003) and residence in the iodine-deficient region (51.7% vs. 38.8%; p = 0.012); they had a higher proportion of longer delays to consultation (47% vs. 20%; p < 0.001), but a higher rate of normal thyroid function (85.5% vs. 3 1.3%; p < 0.001). Thyroid nodules were associated with the delay to consultation (for duration ≥ three years, OR: 6.560 [95% CI: 3.525–12.208)], multiparity (present vs. absent: 2.863 [1.475–5.557]) and family history of goiter (present vs. absent: 2.086 [95% CI:1.231–3.534]) in female patients alone. The high frequency of thyroid nodules observed requires measures aimed at early detection in the population, the training of doctors involved in the management and the strengthening of technical platforms in our hospitals.
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spelling pubmed-97378772022-12-11 The Spectrum of Thyroid Nodules at Kinshasa University Hospital, Democratic Republic of Congo: A Cross-Sectional Study Bukasa, John Kakamba Bayauli-Mwasa, Pascal Mbunga, Branly Kilola Bangolo, Ayrton Kavula, Wivine Mukaya, Jean Bindingija, Joseph M’Buyamba-Kabangu, Jean-René Int J Environ Res Public Health Article We analyzed the spectrum of thyroid nodules in patients attending the endocrinology unit care of the Kinshasa University Hospital and assessed their associated factors. We conducted a cross-sectional study, performing descriptive statistics and logistic regression. From the 888 enrolled patients, thyroid nodules were detected in 658 patients (74.1%), as mononodules in 22.5% and multiple nodules in 77.5%. Thyroid function was normal in 71.3% cases, while hyperthyroidism and hypothyroidism were found in 26.1% and 2.6% of cases, respectively. Women were more affected than men (75.1% vs. 63.6%; p = 0.03). Patients with thyroid nodules were older (44 ± 12 vs. 38 ± 12 years; p < 0.001), with a family history of goiter (38.3% vs. 27.4%; p = 0.003) and residence in the iodine-deficient region (51.7% vs. 38.8%; p = 0.012); they had a higher proportion of longer delays to consultation (47% vs. 20%; p < 0.001), but a higher rate of normal thyroid function (85.5% vs. 3 1.3%; p < 0.001). Thyroid nodules were associated with the delay to consultation (for duration ≥ three years, OR: 6.560 [95% CI: 3.525–12.208)], multiparity (present vs. absent: 2.863 [1.475–5.557]) and family history of goiter (present vs. absent: 2.086 [95% CI:1.231–3.534]) in female patients alone. The high frequency of thyroid nodules observed requires measures aimed at early detection in the population, the training of doctors involved in the management and the strengthening of technical platforms in our hospitals. MDPI 2022-12-03 /pmc/articles/PMC9737877/ /pubmed/36498276 http://dx.doi.org/10.3390/ijerph192316203 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Bukasa, John Kakamba
Bayauli-Mwasa, Pascal
Mbunga, Branly Kilola
Bangolo, Ayrton
Kavula, Wivine
Mukaya, Jean
Bindingija, Joseph
M’Buyamba-Kabangu, Jean-René
The Spectrum of Thyroid Nodules at Kinshasa University Hospital, Democratic Republic of Congo: A Cross-Sectional Study
title The Spectrum of Thyroid Nodules at Kinshasa University Hospital, Democratic Republic of Congo: A Cross-Sectional Study
title_full The Spectrum of Thyroid Nodules at Kinshasa University Hospital, Democratic Republic of Congo: A Cross-Sectional Study
title_fullStr The Spectrum of Thyroid Nodules at Kinshasa University Hospital, Democratic Republic of Congo: A Cross-Sectional Study
title_full_unstemmed The Spectrum of Thyroid Nodules at Kinshasa University Hospital, Democratic Republic of Congo: A Cross-Sectional Study
title_short The Spectrum of Thyroid Nodules at Kinshasa University Hospital, Democratic Republic of Congo: A Cross-Sectional Study
title_sort spectrum of thyroid nodules at kinshasa university hospital, democratic republic of congo: a cross-sectional study
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9737877/
https://www.ncbi.nlm.nih.gov/pubmed/36498276
http://dx.doi.org/10.3390/ijerph192316203
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