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A Prospective Validation Study of the Functional Bedside Aspiration Screen with Endoscopy: Is It Clinically Applicable in Acute Stroke?

The purpose of this study was to investigate the reliability of the novel Functional Bedside Aspiration Screen (FBAS) to predict aspiration risk in acute stroke and to guide initial therapy needs. We conducted a prospective validation study of the FBAS 10-point scale in 101 acute ischemic stroke pat...

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Autores principales: Kassubek, Rebecca, Lindner-Pfleghar, Beate, Virvidaki, Ioanna Eleni, Kassubek, Jan, Althaus, Katharina, Weber, Antonia Maria, Dimakopoulos, Georgios, Milionis, Haralampos, Nasios, Grigorios
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9737958/
https://www.ncbi.nlm.nih.gov/pubmed/36498662
http://dx.doi.org/10.3390/jcm11237087
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author Kassubek, Rebecca
Lindner-Pfleghar, Beate
Virvidaki, Ioanna Eleni
Kassubek, Jan
Althaus, Katharina
Weber, Antonia Maria
Dimakopoulos, Georgios
Milionis, Haralampos
Nasios, Grigorios
author_facet Kassubek, Rebecca
Lindner-Pfleghar, Beate
Virvidaki, Ioanna Eleni
Kassubek, Jan
Althaus, Katharina
Weber, Antonia Maria
Dimakopoulos, Georgios
Milionis, Haralampos
Nasios, Grigorios
author_sort Kassubek, Rebecca
collection PubMed
description The purpose of this study was to investigate the reliability of the novel Functional Bedside Aspiration Screen (FBAS) to predict aspiration risk in acute stroke and to guide initial therapy needs. We conducted a prospective validation study of the FBAS 10-point scale in 101 acute ischemic stroke patients. Outcome measures were compared with the Penetration Aspiration Scale (PAS) via the Flexible Endoscopic Swallowing Study. Correlations with the Functional Oral Intake Scale (FOIS) and the Therapy Requirement Scale (TRS) were analyzed. We observed a 65.8% sensitivity and 70.2% specificity (p = 0.004) for predicting penetration risk (for PAS score ≥ 3) and a 73% sensitivity and 62% specificity for predicting aspiration risk (PAS score ≥ 6). For patients with a modified ranking scale 0–2 (n = 44) on admission, the predictive measurements of the FBAS yielded sensitivity and specificity values of 66.7% and 88.6% (p = 0.011). A significant negative correlation was found with PAS measurements, whereas a positive correlation was observed regarding FOIS. Significantly lower FBAS scores were observed in patients with high requirements for therapeutic interventions and dietary modification. FBAS may be regarded as an alternative time-efficient clinical support tool in settings in which instrumentation is not directly accessible. Further studies including a larger cohort of acute stroke patients with more severe neurological deficits are necessary.
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spelling pubmed-97379582022-12-11 A Prospective Validation Study of the Functional Bedside Aspiration Screen with Endoscopy: Is It Clinically Applicable in Acute Stroke? Kassubek, Rebecca Lindner-Pfleghar, Beate Virvidaki, Ioanna Eleni Kassubek, Jan Althaus, Katharina Weber, Antonia Maria Dimakopoulos, Georgios Milionis, Haralampos Nasios, Grigorios J Clin Med Article The purpose of this study was to investigate the reliability of the novel Functional Bedside Aspiration Screen (FBAS) to predict aspiration risk in acute stroke and to guide initial therapy needs. We conducted a prospective validation study of the FBAS 10-point scale in 101 acute ischemic stroke patients. Outcome measures were compared with the Penetration Aspiration Scale (PAS) via the Flexible Endoscopic Swallowing Study. Correlations with the Functional Oral Intake Scale (FOIS) and the Therapy Requirement Scale (TRS) were analyzed. We observed a 65.8% sensitivity and 70.2% specificity (p = 0.004) for predicting penetration risk (for PAS score ≥ 3) and a 73% sensitivity and 62% specificity for predicting aspiration risk (PAS score ≥ 6). For patients with a modified ranking scale 0–2 (n = 44) on admission, the predictive measurements of the FBAS yielded sensitivity and specificity values of 66.7% and 88.6% (p = 0.011). A significant negative correlation was found with PAS measurements, whereas a positive correlation was observed regarding FOIS. Significantly lower FBAS scores were observed in patients with high requirements for therapeutic interventions and dietary modification. FBAS may be regarded as an alternative time-efficient clinical support tool in settings in which instrumentation is not directly accessible. Further studies including a larger cohort of acute stroke patients with more severe neurological deficits are necessary. MDPI 2022-11-29 /pmc/articles/PMC9737958/ /pubmed/36498662 http://dx.doi.org/10.3390/jcm11237087 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Kassubek, Rebecca
Lindner-Pfleghar, Beate
Virvidaki, Ioanna Eleni
Kassubek, Jan
Althaus, Katharina
Weber, Antonia Maria
Dimakopoulos, Georgios
Milionis, Haralampos
Nasios, Grigorios
A Prospective Validation Study of the Functional Bedside Aspiration Screen with Endoscopy: Is It Clinically Applicable in Acute Stroke?
title A Prospective Validation Study of the Functional Bedside Aspiration Screen with Endoscopy: Is It Clinically Applicable in Acute Stroke?
title_full A Prospective Validation Study of the Functional Bedside Aspiration Screen with Endoscopy: Is It Clinically Applicable in Acute Stroke?
title_fullStr A Prospective Validation Study of the Functional Bedside Aspiration Screen with Endoscopy: Is It Clinically Applicable in Acute Stroke?
title_full_unstemmed A Prospective Validation Study of the Functional Bedside Aspiration Screen with Endoscopy: Is It Clinically Applicable in Acute Stroke?
title_short A Prospective Validation Study of the Functional Bedside Aspiration Screen with Endoscopy: Is It Clinically Applicable in Acute Stroke?
title_sort prospective validation study of the functional bedside aspiration screen with endoscopy: is it clinically applicable in acute stroke?
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9737958/
https://www.ncbi.nlm.nih.gov/pubmed/36498662
http://dx.doi.org/10.3390/jcm11237087
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