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Lymphocyte Classification from Hoechst Stained Slides with Deep Learning

SIMPLE SUMMARY: We train a deep neural network model to identify CD3 expressing cells from Hoechst stained slides only, without the need for costly immunofluorescence. Using interpretability techniques to understand what the model has learned, we find that morphological features in the nuclear chrom...

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Detalles Bibliográficos
Autores principales: Cooper, Jessica, Um, In Hwa, Arandjelović, Ognjen, Harrison, David J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9738034/
https://www.ncbi.nlm.nih.gov/pubmed/36497439
http://dx.doi.org/10.3390/cancers14235957