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Understanding In Vitro Pathways to Drug Discovery for TDP-43 Proteinopathies

The use of cellular models is a common means to investigate the potency of therapeutics in pre-clinical drug discovery. However, there is currently no consensus on which model most accurately replicates key aspects of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) pathology, s...

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Detalles Bibliográficos
Autores principales:	Cheng, Hei W. A., Callis, Timothy B., Montgomery, Andrew P., Danon, Jonathan J., Jorgensen, William T., Ke, Yazi D., Ittner, Lars M., Werry, Eryn L., Kassiou, Michael
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9738080/ https://www.ncbi.nlm.nih.gov/pubmed/36499097 http://dx.doi.org/10.3390/ijms232314769

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