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The BRCAness Landscape of Cancer

BRCAness refers to the damaged homologous recombination (HR) function due to the defects in HR-involved non-BRCA1/2 genes. BRCAness is the important marker for the use of synthetic lethal-based PARP inhibitor therapy in breast and ovarian cancer treatment. The success provides an opportunity of appl...

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Detalles Bibliográficos
Autores principales:	Guo, Maoni, Wang, San Ming
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9738094/ https://www.ncbi.nlm.nih.gov/pubmed/36497135 http://dx.doi.org/10.3390/cells11233877

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