Cargando…

Salvage Chemotherapy with Cisplatin, Ifosfamide, and Paclitaxel in Aggressive Variant of Metastatic Castration-Resistant Prostate Cancer

Significant progress has been achieved in the treatment of metastatic castration-resistant prostate cancer (mCRPC). However, results in patients with aggressive variant prostate cancer (AVPC) have been disappointing. Here, we report retrospectively collected data from intensively pretreated AVPC pat...

Descripción completa

Detalles Bibliográficos
Autores principales:	von Amsberg, Gunhild, Zilles, Mirjam, Mansour, Wael, Gild, Philipp, Alsdorf, Winfried, Kaune, Moritz, Böckelmann, Lukas, Hauschild, Jessica, Krisp, Christoph, Rohlfing, Tina, Saygi, Ceren, Alawi, Malik, Zielinski, Alexandra, Langebrake, Claudia, Oh-Hohenhorst, Su Jung, Perner, Sven, Tilki, Derya, Schlüter, Hartmut, Graefen, Markus, Dyshlovoy, Sergey A., Bokemeyer, Carsten
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9738104/ https://www.ncbi.nlm.nih.gov/pubmed/36499277 http://dx.doi.org/10.3390/ijms232314948

Ejemplares similares

Immunotherapy in Advanced Prostate Cancer—Light at the End of the Tunnel?
por: von Amsberg, Gunhild, et al.
Publicado: (2022)

Efficacy and Mechanism of Action of Marine Alkaloid 3,10-Dibromofascaplysin in Drug-Resistant Prostate Cancer Cells
por: Dyshlovoy, Sergey A., et al.
Publicado: (2020)

Inspired by Sea Urchins: Warburg Effect Mediated Selectivity of Novel Synthetic Non-Glycoside 1,4-Naphthoquinone-6S-Glucose Conjugates in Prostate Cancer
por: Dyshlovoy, Sergey A., et al.
Publicado: (2020)

New diterpenes from the marine sponge Spongionella sp. overcome drug resistance in prostate cancer by inhibition of P-glycoprotein
por: Dyshlovoy, Sergey A., et al.
Publicado: (2022)

Marine alkaloid monanchoxymycalin C: a new specific activator of JNK1/2 kinase with anticancer properties
por: Dyshlovoy, Sergey A., et al.
Publicado: (2020)

Polyphenolic Compounds from Lespedeza Bicolor Root Bark Inhibit Progression of Human Prostate Cancer Cells via Induction of Apoptosis and Cell Cycle Arrest
por: Dyshlovoy, Sergey A., et al.
Publicado: (2020)

Activity of New Synthetic (2-Chloroethylthio)-1,4-naphthoquinones in Prostate Cancer Cells
por: Dyshlovoy, Sergey A., et al.
Publicado: (2021)

Successful Targeting of the Warburg Effect in Prostate Cancer by Glucose-Conjugated 1,4-Naphthoquinones
por: Dyshlovoy, Sergey A., et al.
Publicado: (2019)

Cytotoxic N-Methylpretrichodermamide B Reveals Anticancer Activity and Inhibits P-Glycoprotein in Drug-Resistant Prostate Cancer Cells
por: Dyshlovoy, Sergey A., et al.
Publicado: (2022)

Urupocidin C: a new marine guanidine alkaloid which selectively kills prostate cancer cells via mitochondria targeting
por: Dyshlovoy, Sergey A., et al.
Publicado: (2020)

Study of Structure–Activity Relationships of the Marine Alkaloid Fascaplysin and Its Derivatives as Potent Anticancer Agents
por: Zhidkov, Maxim E., et al.
Publicado: (2022)

New Marine Fungal Deoxy-14,15-Dehydroisoaustamide Resensitizes Prostate Cancer Cells to Enzalutamide
por: Dyshlovoy, Sergey A., et al.
Publicado: (2023)

The marine triterpene glycoside frondoside A induces p53-independent apoptosis and inhibits autophagy in urothelial carcinoma cells
por: Dyshlovoy, Sergey A., et al.
Publicado: (2017)

Standardized Supportive Care Documentation Improves Safety of High‐Dose Methotrexate Treatment
por: Alsdorf, Winfried H., et al.
Publicado: (2020)

New Guanidine Alkaloids Batzelladines O and P from the Marine Sponge Monanchora pulchra Induce Apoptosis and Autophagy in Prostate Cancer Cells
por: Dyshlovoy, Sergey A., et al.
Publicado: (2022)

New Bioactive β-Resorcylic Acid Derivatives from the Alga-Derived Fungus Penicillium antarcticum KMM 4685
por: Leshchenko, Elena V., et al.
Publicado: (2023)

Aaptamines from the Marine Sponge Aaptos sp. Display Anticancer Activities in Human Cancer Cell Lines and Modulate AP-1-, NF-κB-, and p53-Dependent Transcriptional Activity in Mouse JB6 Cl41 Cells
por: Dyshlovoy, Sergey A., et al.
Publicado: (2014)

Synthesis and anticancer activity of the derivatives of marine compound rhizochalin in castration resistant prostate cancer
por: Dyshlovoy, Sergey A., et al.
Publicado: (2018)

AB0/Rhesus Blood Group Does Not Influence Clinicopathological Tumor Characteristics or Oncological Outcome in Patients Undergoing Radical Prostatectomy
por: Oh, Su Jung, et al.
Publicado: (2017)

The Inhibitory Activity of Luzonicosides from the Starfish Echinaster luzonicus against Human Melanoma Cells
por: Malyarenko, Olesya S., et al.
Publicado: (2017)

Total Syntheses and Preliminary Biological Evaluation of Brominated Fascaplysin and Reticulatine Alkaloids and Their Analogues
por: Zhidkov, Maxim E., et al.
Publicado: (2019)

Sea Anemone Heteractis crispa Actinoporin Demonstrates In Vitro Anticancer Activities and Prevents HT-29 Colorectal Cancer Cell Migration
por: Kvetkina, Aleksandra, et al.
Publicado: (2020)

New Trisulfated Steroids from the Vietnamese Marine Sponge Halichondria vansoesti and Their PSA Expression and Glucose Uptake Inhibitory Activities
por: Tabakmakher, Kseniya M., et al.
Publicado: (2019)

Marine alkaloid Monanchocidin a overcomes drug resistance by induction of autophagy and lysosomal membrane permeabilization
por: Dyshlovoy, Sergey A., et al.
Publicado: (2015)

Guanidine Alkaloids from the Marine Sponge Monanchora pulchra Show Cytotoxic Properties and Prevent EGF-Induced Neoplastic Transformation in Vitro
por: Dyshlovoy, Sergey A., et al.
Publicado: (2016)

The growing pains of ifosfamide
por: Sprangers, Ben, et al.
Publicado: (2020)

Second-Generation Antiandrogen Therapy Radiosensitizes Prostate Cancer Regardless of Castration State through Inhibition of DNA Double Strand Break Repair
por: Elsesy, Mohamed E., et al.
Publicado: (2020)

The anti-tumour activity of ifosfamide on heterotransplanted testicular cancer cell lines remains unaltered by the uroprotector mesna.
por: Bokemeyer, C., et al.
Publicado: (1994)

Marine compound rhizochalinin shows high in vitro and in vivo efficacy in castration resistant prostate cancer
por: Dyshlovoy, Sergey A., et al.
Publicado: (2016)

Preclinical patient‐derived modeling of castration‐resistant prostate cancer facilitates individualized assessment of homologous recombination repair deficient disease
por: Elsesy, Mohamed E., et al.
Publicado: (2023)

Ifosfamide nephrotoxicity in adult patients
por: Ensergueix, Gaël, et al.
Publicado: (2019)

Silibinin protects against cisplatin-induced nephrotoxicity without compromising cisplatin or ifosfamide anti-tumour activity.
por: Bokemeyer, C., et al.
Publicado: (1996)

Possible Role of Circulating Tumour Cells for Prediction of Salvage Lymph Node Dissection Outcome in Patients with Early Prostate Cancer Recurrence
por: Knipper, Sophie, et al.
Publicado: (2021)

Pretrichodermamides D–F from a Marine Algicolous Fungus Penicillium sp. KMM 4672
por: Yurchenko, Anton N., et al.
Publicado: (2016)

Adjuvant Versus Early Salvage Radiation Therapy After Radical Prostatectomy for pN1 Prostate Cancer and the Risk of Death
por: Tilki, Derya, et al.
Publicado: (2022)

Cytotoxic Marine Alkaloid 3,10-Dibromofascaplysin Induces Apoptosis and Synergizes with Cytarabine Resulting in Leukemia Cell Death
por: Spirin, Pavel, et al.
Publicado: (2021)

Pharmacokinetic Study of Perioperative Intravenous Ifosfamide
por: Van der Speeten, Kurt, et al.
Publicado: (2011)

The interaction of ifosfamide and aprepitant in gynecologic malignancies()
por: Shindorf, Mackenzie L., et al.
Publicado: (2013)

Ifosfamide-Induced Malignancy of Ureter and Bladder
por: Sannu, Aparna, et al.
Publicado: (2017)

Partial Fanconi Syndrome Induced by Ifosfamide
por: Das, Sulagna, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_mhr99tcv77m4t6bv27kokk9ldi