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Preclinical Assessment of Immunogenicity and Protectivity of Novel ROR1 Fusion Proteins in a Mouse Tumor Model

SIMPLE SUMMARY: Receptor tyrosine kinase-like orphan receptor 1 (ROR1) is a tumor-associated antigen reported to be overexpressed in a variety of malignancies. The aim of this study is preclinical evaluation of various ROR1 fusion proteins as novel cancer vaccines in a fully syngeneic mouse tumor mo...

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Detalles Bibliográficos
Autores principales: Hassannia, Hadi, Amiri, Mohammad Mehdi, Ghaedi, Mojgan, Sharifian, Ramezan-Ali, Golsaz-Shirazi, Forough, Jeddi-Tehrani, Mahmood, Shokri, Fazel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9738141/
https://www.ncbi.nlm.nih.gov/pubmed/36497309
http://dx.doi.org/10.3390/cancers14235827