Cargando…

Lupane Triterpene Derivatives Improve Antiproliferative Effect on Leukemia Cells through Apoptosis Induction

Leukemia is one of the most frequent types of cancer. No effective treatment currently exists, driving a search for new compounds. Simple structural modifications were made to novel triterpenes isolated from Phoradendron wattii. Of the three resulting derivatives, 3α-methoxy-24-hydroxylup-20(29)-en-...

Descripción completa

Detalles Bibliográficos
Autores principales:	Valencia-Chan, Lía S., Estrada-Alfaro, Neptis, Ceballos-Cruz, Jimmy Josué, Torres-Tapia, Luis W., Peraza-Sánchez, Sergio R., Moo-Puc, Rosa E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9738192/ https://www.ncbi.nlm.nih.gov/pubmed/36500355 http://dx.doi.org/10.3390/molecules27238263

Ejemplares similares

Apoptotic and Cell Cycle Effects of Triterpenes Isolated from Phoradendron wattii on Leukemia Cell Lines
por: Valencia-Chan, Lía S., et al.
Publicado: (2022)

Lupane Triterpenes from the Leaves of Acanthopanax gracilistylus
por: Li, Xiao-Jun, et al.
Publicado: (2018)

Bioactive Oleanane, Lupane and Ursane Triterpene Acid Derivatives
por: e Silva, Maria de L., et al.
Publicado: (2012)

3-Pyridinylidene Derivatives of Chemically Modified Lupane and Ursane Triterpenes as Promising Anticancer Agents by Targeting Apoptosis
por: Kazakova, Oxana, et al.
Publicado: (2021)

Selective binding modes and allosteric inhibitory effects of lupane triterpenes on protein tyrosine phosphatase 1B
por: Jin, Tiantian, et al.
Publicado: (2016)

Lupane-type triterpenes and their anti-cancer activities against most common malignant tumors: A review
por: Cháirez-Ramírez, MH, et al.
Publicado: (2016)

Cytotoxic activities of naturally occurring oleanane-, ursane-, and lupane-type triterpenes on HepG2 and AGS cells
por: Yang, Heejung, et al.
Publicado: (2017)

Biocatalysis in the Chemistry of Lupane Triterpenoids
por: Bachořík, Jan, et al.
Publicado: (2021)

A lupane-triterpene isolated from Combretum leprosum Mart. fruit extracts that interferes with the intracellular development of Leishmania (L.) amazonensis in vitro
por: Teles, Carolina Bioni Garcia, et al.
Publicado: (2015)

Antiproliferative and Antiestrogenic Activities of Bonediol an Alkyl Catechol from Bonellia macrocarpa
por: Moo-Puc, Rosa, et al.
Publicado: (2015)

Anti-Toxoplasma gondii effect of lupane-type triterpenes from the bark of black alder (Alnus glutinosa) and identification of a potential target by reverse docking
por: Darme, Pierre, et al.
Publicado: (2022)

Synthesis, Optical Properties, and Antiproliferative Evaluation of NBD-Triterpene Fluorescent Probes
por: Medina-O’Donnell, Marta, et al.
Publicado: (2022)

Isolation and Identification of Cytotoxic Compounds from Aeschynomene fascicularis, a Mayan Medicinal Plant
por: Caamal-Fuentes, Edgar E., et al.
Publicado: (2015)

Actaticas A−G, Cycloartane Triterpenes From Actaea asiatica With Their Antiproliferative Activity
por: Hu, Meigeng, et al.
Publicado: (2021)

Anti-Proliferative Activities and Apoptosis Induction by Triterpenes Derived from Eriobotrya japonica in Human Leukemia Cell Lines
por: Uto, Takuhiro, et al.
Publicado: (2013)

Uncontrolled hypertension among hypertensive patients on treatment in Lupane District, Zimbabwe, 2012
por: Goverwa, Tafadzwa Priscilla, et al.
Publicado: (2014)

Elesesterpenes A–K: Lupane-type Triterpenoids From the Leaves of Eleutherococcus sessiliflorus
por: Han, Dong, et al.
Publicado: (2022)

Antiproliferative Activity of Triterpene Glycoside Nutrient from Monk Fruit in Colorectal Cancer and Throat Cancer
por: Liu, Can, et al.
Publicado: (2016)

Isolation of the Lanostane Triterpenes Pholiols L–S from Pholiota populnea and Evaluation of Their Antiproliferative and Cytotoxic Activities
por: Yazdani, Morteza, et al.
Publicado: (2023)

Evaluation of Cytotoxicity and α-Glucosidase Inhibitory Activity of Amide and Polyamino-Derivatives of Lupane Triterpenoids
por: Kazakova, Oxana B., et al.
Publicado: (2020)

Decoration of A-Ring of a Lupane-Type Triterpenoid with Different Oxygen and Nitrogen Heterocycles
por: Sousa, Joana L. C., et al.
Publicado: (2022)

Antileishmanial Activity of Semisynthetic Lupane Triterpenoids Betulin and Betulinic Acid Derivatives: Synergistic Effects with Miltefosine
por: Sousa, Maria C., et al.
Publicado: (2014)

New Investigations with Lupane Type A-Ring Azepane Triterpenoids for Antimycobacterial Drug Candidate Design
por: Kazakova, Oxana, et al.
Publicado: (2021)

Cardiac Protection of a Novel Lupane-Type Triterpenoid from Injuries Induced by Hypoxia–Reperfusion
por: Guo, Beibei, et al.
Publicado: (2022)

A feasibility assessment of utilizing concentrated solar power (CSP) in the Zimbabwean regions of Hwange and Lupane
por: Mutume, Bruce
Publicado: (2023)

A Morinda royoc Root Extract and Fractions Exhibit Antigiardial Activity without Affecting Cell Viability
por: Quintal-Novelo, Carlos, et al.
Publicado: (2022)

P01.33. A new development of Triterpene Acids-containing extracts from Viscum album L. displays synergistic induction of apoptosis in childhood leukemia
por: Delebinski, C, et al.
Publicado: (2012)

Three new C-27-carboxylated-lupane-triterpenoid derivatives from Potentilla discolor Bunge and their in vitro antitumor activities
por: Zhang, Jing, et al.
Publicado: (2017)

Selective hepatitis B and D virus entry inhibitors from the group of pentacyclic lupane-type betulin-derived triterpenoids
por: Kirstgen, Michael, et al.
Publicado: (2020)

Antiproliferative Activity and Apoptosis Induction of Crude Extract and Fractions of Avicennia Marina
por: Momtazi-borojeni, Amir abbas, et al.
Publicado: (2013)

Antiproliferative activity of new pentacyclic triterpene and a saponin from Gladiolus segetum Ker-Gawl corms supported by molecular docking study
por: Abd El-kader, Adel M., et al.
Publicado: (2020)

Ceramide as a Target of Marine Triterpene Glycosides for Treatment of Human Myeloid Leukemia
por: Yun, Seong-Hoon, et al.
Publicado: (2016)

State-of-the-Art and Opportunities for Bioactive Pentacyclic Triterpenes from Native Mexican Plants
por: Alfaro-Almaguer, Juan Antonio, et al.
Publicado: (2022)

Triterpene einschließlich Steroide
por: Sticher, O.
Publicado: (2007)

Triterpene einschließlich Steroide
por: Sticher, Otto
Publicado: (2009)

Immunomodulatory properties of triterpenes
por: Renda, Gülin, et al.
Publicado: (2021)

Cytotoxicity, Antiproliferative Effects, and Apoptosis Induction of Methanolic Extract of Cynometra cauliflora Linn. Whole Fruit on Human Promyelocytic Leukemia HL-60 Cells
por: Tajudin, T-Johari S. A., et al.
Publicado: (2012)

Dammarane triterpenes targeting α-synuclein: biological activity and evaluation of binding sites by molecular docking
por: Cornejo, Alberto, et al.
Publicado: (2020)

Agronomic and chemical performance of field‐grown tobacco engineered for triterpene and methylated triterpene metabolism
por: Jiang, Zuodong, et al.
Publicado: (2018)

De Novo Transcriptome Sequencing of Codonopsis lanceolata for Identification of Triterpene Synthase and Triterpene Acetyltransferase
por: Choi, Han-Bin, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_e4igifv605p6vnrv1794h2ed4g